Allopurinol Contraindications detrol
uses, directions, precautions, drug interactions or Subsequent adjustment of doses of mercaptopurine or azathioprine should be made on the basis of therapeutic response and the appearance of toxic effects (see Allopurinol tablets are not known to alter the accuracy of laboratory tests.Allopurinol and oxipurinol have been found in the milk of a mother who was receiving Allopurinol tablets. The explanation for this decrease has not been determined but may be due in part to initiating therapy more gradually (see Massive overdosing or acute poisoning by Allopurinol tablets has not been reported.The dosage of Allopurinol tablets to accomplish full control of gout and to lower serum uric acid to normal or near-normal levels varies with the severity of the disease. Allopurinol can also alter the amounts of certain medications in your blood. In some instances a skin rash may be followed by more severe hypersensitivity reactions such as exfoliative, urticarial, and purpuric lesions, as well as Stevens-Johnson syndrome (erythema multiforme exudativum), and/or generalized vasculitis, irreversible hepatotoxicity, and, on rare occasions, death.An increase in acute attacks of gout has been reported during the early stages of administration of Allopurinol tablets, even when normal or subnormal serum uric acid levels have been attained. IT IS NOT RECOMMENDED FOR THE TREATMENT OF ASYMPTOMATIC HYPERURICEMIA.Patients who have developed a severe reaction to Allopurinol tablets should not be restarted on the drug.Allopurinol TABLETS SHOULD BE DISCONTINUED AT THE FIRST APPEARANCE OF SKIN RASH OR OTHER SIGNS WHICH MAY INDICATE AN ALLERGIC REACTION. In addition, it is recommended that the patient start with a low dose of Allopurinol tablets (100 mg daily) and increase at weekly intervals by 100 mg until a serum uric acid level of 6 mg/dL or less is attained but without exceeding the maximum recommended dose (800 mg per day). Find out what health conditions may be a health risk when taken with Detrol LA Oral copyrighted by First Databank, Inc. Find out what health conditions may be a health risk when taken with allopurinol oral
Allopurinol, USP is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d]pyrimidin-4-one. The mobilization of urates from tissue deposits which cause fluctuations in the serum uric acid levels may be a possible explanation for these episodes. Skin rash is a frequently reported adverse reaction in patients receiving allopurinol. Dosage requirements in excess of 300 mg should be administered in divided doses. or commencing or discontinuing any course of treatment. WARNINGS: ZYLOPRIM SHOULD BE DISCONTINUED AT THE FIRST APPEARANCE OF SKIN A healthcare professional Hypersensitivity to allopurinol.
is intended to supplement, not substitute for, the CONTRAINDICATIONS.
WebMD does not provide medical advice, diagnosis or treatment. This copyrighted As a result of xanthine oxidase inhibition, the serum concentration of hypoxanthine plus xanthine in patients receiving Allopurinol tablets for treatment of hyperuricemia is usually in the range of 0.3 to 0.4 mg/dL compared to a normal level of approximately 0.15 mg/dL. WebMD provides common contraindications for allopurinol oral. provider and is not for distribution, except as may CONDITIONS OF USE: The information in this database The attacks usually become shorter and less severe after several months of therapy.
Detrol Tablets are contraindicated in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma.
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