Angiotensin receptor blocker vantin
National Natural Science Foundation of China, Chinese Academy of Medical SciencesNational Natural Science Foundation of China, Chinese Academy of Medical SciencesAll relevant ethical guidelines have been followed; any necessary IRB and/or ethics committee approvals have been obtained and details of the IRB/oversight body are included in the manuscript.All necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived.I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. Background The novel coronavirus (CoV) severe acute respiratory syndrome (SARS)-CoV-2 outbreak started at the end of 2019 in Wuhan, China, and spread over 100 countries. Among the elderly (age>65) COVID-19 patients with hypertension comorbidity, the risk of COVID-19-S (severe disease) was significantly decreased in patients who took ARB drugs prior to hospitalization compared to patients who took no drugs (OR=0.343, 95% CI 0.128-0.916, p=0.025). The meta-analysis showed that ARB use has positive effects associated with morbidity and mortality of pneumonia. The choice of angiotensin-II receptor blocker (also known as angiotensin-II receptor antagonist) usually depends on the person's co-morbidities, local recommendations, and cost. Background. Angiotensin II receptor blockers (ARBs) have similar effects as ACE inhibitors, another type of blood pressure drug, but work by a different mechanism. A meta-analysis was performed to evaluate the use of ACEI and ARB associated with pneumonia using published studies.
Aims: This retrospective case-control study was aimed at identifying potential independent predictors of severe/lethal COVID-19, including the treatment with Angiotensin-Converting Enzyme inhibitors (ACEi) and/or Angiotensin II Receptor Blockers (ARBs). Also contact your doctor if you have any other symptoms that cause concern.WebMD does not provide medical advice, diagnosis or treatment.Angiotensin II receptor blockers (ARBs) have similar effects as ACE inhibitors, another type of blood pressure drug, but work by a different mechanism. Where possible, prescribe a drug that is taken only once a day and prescribe non-proprietary drugs … ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19, paper suggests. John McCabe, Christine Stork, Danielle Mailloux, Mark Su, Penile angioedema associated with the use of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers, American Journal of Health-System Pharmacy, 10.2146/ajhp070299, 65, 5, (420-421), (2008). Highly selective angiotensin II (Ang II) type 1 (AT(1)) receptor blockers (ARBs) are now available. Elderly (age>65) COVID-19 patients with hypertension comorbidity who are taking ARB anti-hypertension drugs may be less likely to develop severe lung disease compared to patients who take no anti-hypertension drugs. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). The included COVID-19 patients used ACEI, ARB, calcium channel blockers (CCB), beta blockers (BB), or thiazide to treat preexisting hypertension prior to the hospital were compared to patients who did not take any of those drugs. It is controversial, however, whether commonly used anti-hypertensive drugs Angiotensin I converting enzyme inhibitor (ACEI) and Angiotensin II receptor blocker (ARB) shall be continued in the confirmed COVID-19 patients. This study was designed to investigate any difference in disease severity between COVID-19 patients with hypertension comorbidity. SARS-CoV-2 uses the membrane protein Angiotensin I converting enzyme 2(ACE2) as a cell entry receptor.
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