Clarithromycin oral suspension uses genegra

Dosage Adjustments in Patients with Renal ImpairmentTable 3. Other epidemiologic studies evaluating this risk have shown variable results The following adverse reactions have been identified during post approval use of clarithromycin. Reductions in body weight and food consumption was observed in dams at 150 mg/kg/day.

You may report side effects to the FDA at 1-800-332-1088. Clarithromycin demonstrated adverse effects on pregnancy outcome and/or embryo- fetal development, including fetal malformations, in pregnant animals administered oral clarithromycin [see Exacerbation of symptoms of myasthenia gravis and new onset of symptoms of myasthenic syndrome has been reported in patients receiving clarithromycin therapy.Prescribing clarithromycin in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.The following serious adverse reactions are described below and elsewhere in the labeling:Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.Based on pooled data across all indications, the most frequent adverse reactions for both adult and pediatric populations observed in clinical trials are abdominal pain, diarrhea, nausea, vomiting and dysgeusia. The potential for these adverse reactions should be taken into account before patients drive or use machines.Advise patients who have coronary artery disease to continue medications and lifestyle modifications for their coronary artery disease because clarithromycin may be associated with increased risk for mortality years after the end of clarithromycin treatment. Clarithromycin can be discontinued when the patient is considered at low risk of disseminated infection.Decrease the dose of clarithromycin by 50 % when co-administered with atazanavir [see The supplied clarithromycin granules must be reconstituted with water prior to administration of clarithromycin for oral suspension. Bronchitis: 250mg–500mg every 12hrs for 7–14 days. Reduced body weight and food consumption were observed in dams at 160 mg/kg/day but there was no evidence of adverse developmental effects at any dose (≤1 times MRHD based on body surface area comparison).In pregnant rabbits, clarithromycin administered during organogenesis (GD 6 to 18) at oral doses of 10, 35, or 125 mg/kg/day resulted in reduced maternal food consumption and decreased body weight at the highest dose, with no evidence of any adverse developmental effects at any dose (≤ 2 times MRHD based on body surface area comparison). It is recommended to prescribe the lowest registered dose if concomitant use cannot be avoided.In one clinical trial evaluating treatment with clarithromycin on outcomes in patients with coronary artery disease, an increase in risk of all-cause mortality one year or more after the end of treatment was observed in patients randomized to receive clarithromycin.If CDAD is suspected or confirmed, ongoing antibacterial use not directed against Based on findings from animal studies, clarithromycin is not recommended for use in pregnant women except in clinical circumstances where no alternative therapy is appropriate. However, this medicine will not work for colds, flu, or other virus infections. Sildenafil, tadalafil, vardenafil: not recommended. Baseline characteristics between treatment arms were similar with the exception of median CFU counts being at least 1 log higher in the clarithromycin, ethambutol, and clofazime arm.Compared to prior experience with clarithromycin monotherapy, the two-drug regimen of clarithromycin and ethambutol extended the time to microbiologic relapse, largely through suppressing the emergence of clarithromycin resistant strains.

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