Imdur twice daily dosing speman

Initially, 2 tablets twice daily, followed by 1 tablet twice daily. The recommended regimen of isosorbide mononitrate tablets is 20 mg twice daily, with the doses seven hours apart.

If the dose is one three times daily, take one every 6 hours. The recommended starting dose of Imdur Tablets is 30 mg (given as a single 30 mg tablet or as 1/2 of a 60 mg tablet) or 60 mg (given as a single tablet) once daily. The maximum dose is 3 tablets isosorbide mononitrate 40 mg per day. This information is intended for use by health professionalsSage House, 319 Pinner Road, North Harrow, Middlesex, HA1 4HF, UKTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Diagnosis and treatment of chest pain depends upon the cause and clinical presentation of the patient's chest pain.Angina is chest pain due to inadequate blood supply to the heart. After several days, the dosage may be increased to 120 mg (given as a single 120 mg tablet or as two 60 mg tablets) once daily. Thirty-seven patients with chronic, stable angina pectoris were included in a randomized, double-blind cross-over study to assess the efficacy of once- and twice-daily dosage regimens of 60 mg isosorbide-5-mononitrate, in a controlled-release formulation (5-ISMN Durules, Astra). Imdur dosing information. Duration of treatment may vary from 4 to 6 months. The prognosis of a patient with congestive heart failure depends on the stage of the heart failure and the overall condition of the individual.Dizziness is a symptom that often applies to a variety of sensations including lightheadedness and vertigo. Dosing: Angina: Regular release tablet: 5-10 mg twice daily with the two doses given 7 hours apart (8am and 3pm) to decrease tolerance development - then titrate to 10 mg twice daily in first 2-3 days.Extended release tablet: Initial: 30-60 mg given in the morning as a single dose.Titrate upward as needed, giving at least 3 days between increases. The dose can be increased to 10 mg twice daily after 2 to 3 days. The recommended starting dose of isosorbide mononitrate is 5 to 10 mg of immediate release tablets twice daily. This provides a nitrate-free period of 6 – 8 hours. Causes of dizziness include low blood pressure, heart problems, anemia, dehydration, and other medical conditions. Immediate release: 5-10 mg PO twice daily initially (5 mg in small patients) given each dose 7 hr apart; increased to 10 mg PO q12hr by day 2 or 3; maintenance: 20 mg PO q12hr Extended release: 30-60 mg PO once daily in the morning initially; may be increased to 120 mg PO once daily; wait at least 3 days between increases; if warranted may increase up to 240 mg PO once daily (rare)


Initially, 2 tablets twice daily, followed by 1 tablet twice daily. Prevention of angina pectoris caused by coronary artery diseaseImmediate release: 5-10 mg PO twice daily initially (5 mg in small patients) given each dose 7 hr apart; increased to 10 mg PO q12hr by day 2 or 3; maintenance: 20 mg PO q12hrExtended release: 30-60 mg PO once daily in the morning initially; may be increased to 120 mg PO once daily; wait at least 3 days between increases; if warranted may increase up to 240 mg PO once daily (rare)PDE-5 inhibitors (eg, avanafil, sildenafil, tadalafil, or vardenafil); concomitant use can cause severe hypotension, syncope, or myocardial ischemiaConcomitant administration with guanylate stimulator riociguat (may cause hypotension)Use caution in acute myocardial infarction, alcohol use, hyperthyroidism, increased intracranial pressure (eg, from head trauma or cerebral hemorrhage; potential contraindication), increased intraocular pressure, postural hypotension, volume depletion, Moderate hypotension, low systolic blood pressure (BP)Not recommended for use in patients with acute myocardial infarction or heart failureMay cause CNS depression, which may in turn impair physical or mental abilities; caution patient about performing tasks that require mental alertness, including operating heavy machineryAvoid use in patients with hypertrophic cardiomyopathy with outflow tract obstruction; nitrates may reduce preload, which can exacerbate obstruction and cause hypotension or syncope and/or worsening of heart failureDo not change brands unintentionally; formulations are not all bioequivalent; extended release formulation not intended for the immediate relief of acute attacks of angina pectorisTreat drug-induced headache with aspirin or acetaminophenProvide nitrate-free interval (10-12 hr or overnight) to prevent development of toleranceSevere hypotension may occur along with paradoxical bradycardia and increased angina pectoris; ethanol can cause severe hypotension with even small doses; avoid excessive, prolonged hypotensionNarrow-angle glaucoma (controversial: may not be clinically significant)Lactation: Unknown whether drug crosses into breast milk; use cautionA: Generally acceptable.

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