Maculopapular rash baclofen

Initially used in the treatment of spasticity, it is now being used in the treatment of alcohol dependence. We report a case series of 4 patients who developed morbiliform rashes after initiation of baclofen. Adverse cutaneous drug reactions are known to occur with many drugs used in psychiatry. They’ll look at where it started and how the rash has spread. The name is a blend of the words “macule,” which are flat discolored skin lesions, and “papule,” which are small raised bumps. Our website services, content, and products are for informational purposes only. 3 It could be said that Maculopapular eruption caused by Acetaminophen is … These trials also demonstrated that baclofen was associated with reductions in withdrawal-related anxiety and alcohol craving. This systematic method offers a sensitive way to monitor ADRs and may be applicable to postmarketing drug surveillance.Baclofen is a gamma amino butyric acid (GABA) derivative that is a specific agonist at GABA-B receptors. The rash generally fades after one to two weeks. Baclofen is a gamma amino butyric acid (GABA) derivative that is a specific agonist at GABA-B receptors. Selected from data included with permission and copyrighted by First Databank, Inc. The between-raters reliability of three attending physicians who independently assessed 28 other prospectively collected cases of alleged ADRs was very high (range: r = 0.76 to 0.87; R(est) = 0.80). A population pharmacokinetic (PK)–pharmacodynamic analysis of the OCDS variation following baclofen administration was performed. These include: This may be a sign of an infection, which may be potentially contagious. If experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionSelected from data included with permission and copyrighted by First Databank, Inc. Skin reactions to Acetaminophen have been reported in the past. For example, a recent US trial failed to demonstrate a robust effect of baclofen in treating alcohol-dependent patients though the relative moderate severity of alcohol-dependence in that trial has been suggested as one factor that may have contributed to the finding. Submitted by ellie on Sun, 2005-08-14 07:59. To study the sleep quality of medical students and it's correlation with various factors Study of mass psychogenic illness in context of tribal India and review of literature. Allergic reactions and minor reactions to drugs generally clear up quickly. The frequency of cutaneous reactions to specific drugs may exceed 10%. None of the covariates tested was able to improve the fit or decrease intersubject variability. Moreover, we describe evidence that viral infection is an important predisposing factor for the development of cutaneous drug reactions upon drug administration. Initially used in the treatment of spasticity, it is now being used in the treatment of alcohol dependence. A maculopapular rash looks like red bumps on a flat, red patch of skin. A 55-year-old white man presented to the hospital for evaluation of abdominal pain and a rash on his bilateral lower extremities. For example, you may develop life-threatening allergic reactions (anaphylaxis) with certain drugs, which causes a skin reaction. A cutaneous maculopapular rash may be linked to several underlying disease/conditions. Healthline Media does not provide medical advice, diagnosis, or treatment. KEY WORDS: baclofen, skin rash, alcohol dependence, adverse reactions, anti-craving. A drug reaction, infection, an autoimmune response, or allergic reaction can cause your body’s immune system to respond and develop maculopapular rashes.It’s best to see a doctor if you break out in a maculopapular rash. Depending on the course of your rash and your history, the doctor may order a blood or urine test.

We report a case series of 4 patients who developed morbiliform rashes after initiation of baclofen.Cutaneous adverse drug reactions (CADRs) in psychiatric pharmacotherapy are common, potentially harmful, and among the most frequent types of adverse events.

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