Propranolol dosage maxalt

The dose of MAXALT should be adjusted in propranolol-treated patients, as propranolol has been shown to increase the plasma AUC of rizatriptan by 70% [see DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGY].

The estimated probability of patients taking a second dose or other medication for migraine over the 24 hours following the initial dose of study treatment is summarized in Efficacy was unaffected by the presence of aura; by the gender, or age of the patient; or by concomitant use of common migraine prophylactic drugs (e.g., beta-blockers, calcium channel blockers, tricyclic antidepressants) or oral contraceptives.

For pediatric patients weighing 40 kg (88 lb) or more, taking propranolol, only a single 5-mg dose of MAXALT is recommended (maximum dose of 5 mg in a 24-hour period). by: Merck Sharp & Dohme Corp., a subsidiary ofRizatriptan benzoate (active ingred.) For more information, ask your doctor or pharmacist.Call your doctor for medical advice about side effects. When rizatriptan (0, 5, 10, or 50 mg/kg/day) was administered orally to pregnant rabbits throughout organogenesis, no adverse fetal effects were observed. If you have these symptoms, do not drive a car, use machinery, or do anything that needs you to be alert.The most common side effects of MAXALT in adults include:Tell your doctor if you have any side effect that bothers you or that does not go away.If you take MAXALT too often, this may result in you getting chronic headaches.

The results from Studies 5 and 6 are summarized in Table 3.The estimated probability of achieving an initial headache response by 2 hours following treatment with MAXALT-MLT in pooled Studies 5 and 6 is depicted in Figure 3.For patients with migraine-associated photophobia and phonophobia at baseline, there was a decreased incidence of these symptoms following administration of MAXALT-MLT as compared to placebo.Two to 24 hours following the initial dose of study treatment, patients were allowed to use additional treatment for pain response in the form of a second dose of study treatment or other medication. The maximum daily dose should not exceed 30 mg in any 24-hour period.
For more information, ask your doctor or pharmacist.Call your doctor for medical advice about side effects. by: Merck Sharp & Dohme Corp., a subsidiary ofEach tablet contains 14.53 mg of rizatriptan benzoate,Each tablet contains 7.265 mg of rizatriptan benzoate, equivalent to 5 mg rizatriptan.Dist. Because the reports include events observed in open studies, the role of MAXALT in their causation cannot be reliably determined.

Patients had to have at least a 6-month history of migraine attacks (with or without aura) usually lasting 3 hours or more (when untreated). MAXALT should not be prescribed to propranolol-treated pediatric patients who weigh less than 40 kg (88 lb) Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. A specific MAO-A inhibitor increased the systemic exposure of rizatriptan and its metabolite [see MAXALT should not be given to patients with ischemic or vasospastic Life-threatening disturbances of cardiac rhythm, including As with other acute migraine therapies, before treating headaches in patients not previously diagnosed as migraineurs, and in migraineurs who present with Reports of transient and permanent blindness and significant partial vision loss have been reported with the use of 5-HTOveruse of acute migraine drugs (e.g., ergotamine, triptans, opioids, or a combination of drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache). Doses greater than 10 mg were associated with an increased incidence of adverse effects.

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