SSRI and heart disease diabecon

AF indicates atrial fibrillation; ARIC, Atherosclerosis Risk in Communities; BMI, body mass index; HF, heart failure; HR, hazard ratio; MI, myocardial infarction; SSRI, selective serotonin reuptake inhibitor.This study did not show a reduced risk of CVD with SSRI usage compared with use of TCAs and other non‐SSRI antidepressants. Background: There are known safety risks with selective serotonin reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs), particularly in regard to cardiovascular safety. SSRIs, SNRIs and Cardiovascular Risk Cory Middendorf, PharmD, MBA, Goodrich Pharmacy. Adverse effects that may last throughout the time the medication is taken include sexual difficulties, nausea, and headache. During the first few weeks of taking an SSRI, patients may actually experience increased anxiety until the drug is fully effective -- usually in 4 to 6 weeks. Start of follow‐up was the date of the visit in which antidepressant medication use was recorded for the first time, while end of follow up was defined as date of the specific CVD occurrence; December 31, 2016; death; or lost to follow‐up, whichever occurred earlier. Follow‐up time was stratified on the basis of the median follow‐up time for subjects not experiencing the event of interest (censored observation).Minimally adjusted models included as covariates age, race/center, sex, and level of education. By continuing to browse this site you are agreeing to our use of cookies.Department of Medicine, Emory University School of Medicine, Atlanta, GADivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GADivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GADivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MNDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MNDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GAEshelman School of Pharmacy, University of North Carolina, Chapel Hill, NCDepartment of Epidemiology and Prevention, Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston‐Salem, NCCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MNDepartment of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GADivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GADepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GADivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GADepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GADepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GAThe association of antidepressant medication type with the risk of cardiovascular disease (Antidepressant medication type (serotonin reuptake inhibitor versus non–serotonin reuptake inhibitor) was not associated with long‐term risk of future cardiovascular disease in a community‐based sample of antidepressant users.Lack of adverse cardiovascular outcomes by type of antidepressant should allay concerns about use of non–serotonin reuptake inhibitor antidepressants in patients who do not respond to serotonin reuptake inhibitors or have unacceptable side effects related to their use.Antidepressants are among the most commonly prescribed medications in the United States, prescribed to ≈15% of adults; however, questions about potential cardiovascular effects with long‐term use persist.In this study, we compared the relative CVD risk of different classes of antidepressants in participants of the ARIC (Atherosclerosis Risk in Communities) study, a community‐based cohort, during a 26‐year study period.

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