Xeloda mechanism of action zofran

They have only done it on a small sample size and it is still very good on those with MGMT, but they said 100% on those without it. Also, have any of you had your tumor tested for MGMT?I'm now in my sixth cycle of CAPTEM chemotherapy, and I have generally been feeling much better and more "normal" during the first or second week of my two-week "rest periods." The use of dexamethasone with chemotherapy medications can benefit cancer patients in several ways. Ondansetron: (Minor) Ondansetron has been associated with QT prolongation and post-marketing reports of torsade de pointes (TdP). These medications may interact and cause very harmful effects. Surgeons felt I had too many tumors in my liver & primary tumor in the head of the pancreas was too big to do surgery at that time so I went on the X+T regimen. I thought maybe I should look into possible variations and preferences of other patients and their pNET specialists. Fatigue too but I've been managing to continue to work full time - just end up going to bed earlier every night, like 8:00 instead of 10:00. It is a tablet that you take by mouth. Cardiovascular events such as myocardial infarction, arrhythmia, and hypertension have been reported during gemcitabine therapy. The Strosberg et al Capecitabine/Temozolomide chemotherapy research journal article in the Jan. 2011 issue of Cancer appears to be the basis for the Cap/Tem (Xeloda/Temodar) chemo protocol. Dr. Strosberg talked about a rest period and that we will evaluate after the next cycle.These chemo protocols have not been around for more than a few years. The research used chemo dosing of 1500mg Capecitabine daily and 200mg Temozolomide daily in the 14 day on/14 day off regimen. I had my CT scan and follow-up appointment today. Selected from … Or will you be given a longer break or rest period at some point, off the drugs, where only periodic scanning will be done? Apparently if it is NOT present then this C/T regime has been extremely effective. A glucocorticosteroid, dexamethasone is an anti-inflammatory drug that treats chemotherapy side effects such as edema, loss of appetite, vomiting, and feelings of nausea. Please feel free to share this with Dr. Strosberg. The fallback position will be to return to lower dosages if necessary. This time, my dosage is less - doing 1500 mg Xeloda and 200 mg Temodar. Be well.Hi - It's great to hear this is working so well for everyone! Do these dosages reflect the same dosages of other patients using this chemo protocol?I think you're right that individual patients will have their dosages modified in certain ways, either to adjust for weight/body size factors, or to adjust for tolerance factors. And how much longer do you expect Dr. Strosburg will keep you on it? The exact mechanism of action of oxaliplatin is not known. My 3 month follow up CT showed 2 definite areas in liver of new tumor growth so I'm back on the X+T. Thanks for the info and "ammo", Dstaud!!! How long have you been on the X+T regimen? I've noticed, however, that it takes me a few days into a new "rest period" before I start feeling better and more "normal. To start a new discussion in this community, It contains a platinum atom complexed with oxalate and diaminocyclohexane (DACH). Enough that surgeons felt I could have the Whipple. I started higher and had to reduce the dosage because my platelet count was too low. I did not expect to see any sizeable changes in primary pancreatic tumor or liver mets after short 3-month time frame on C/T regimens. Select one or more newsletters to continue. Good luck with the higher dosages. Oxaliplatin forms reactive Final decision on choice of chemo regimen was made by me as the patient. There have been very few prospective randomized, controlled research studies for pNETs. Topical zinc oxide is a non-prescription (OTC) over-the-counter) mild astringent with weak antiseptic properties.It is a skin protectant that is used to treat and prevent various skin conditions including minor abrasions, burns, chafing, diaper rash, insect bites, and minor skin irritation.. What brand names are available for zinc oxide? I did two rounds of that and CT showed significant tumor shrinkage.

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