acyclovir ointment dosage tofranil
Avoid getting this medication in your eyes.If this happens, wash right away with plenty of water. In all studies, there was no significant difference between the drug and placebo group in the rate or type of reported adverse reactions nor were there any differences in abnormal clinical laboratory findings.Overdosage by topical application of Acyclovir Ointment USP, 5% is unlikely because of limited transcutaneous absorption (see Apply sufficient quantity to adequately cover all lesions every 3 hours, 6 times per day for 7 days. Apply this medication to skin only. -The recommended dosage, application frequency, and treatment duration of acyclovir topical ointment should not be exceeded. No local intolerance, systemic toxicity, or contact dermatitis were observed. In this uncontrolled study, acyclovir was detected in the blood of 9 patients and in the urine of all patients tested. 31722-968-32 In addition, no drug was detected in blood and urine by radioimmunoassay (sensitivity, 0.01 mcg/mL).The other study included 11 patients with localized varicella zoster infections. The dose size per application will vary depending upon the total lesion area but should approximate a one-half inch ribbon of ointment per 4 square inches of surface area. Each gram of Acyclovir Ointment USP, 5% contains 50 mg acyclovir in a polyethylene glycol base. Acyclovir Ointment USP, 5% is a formulation for topical administration. Acyclovir Ointment USP, 5% is a synthetic nucleoside analogue active against herpes viruses. How to use Acyclovir Ointment. Detailed dosage guidelines and administration information for Zovirax Ointment (acyclovir). 31722-968-31, Includes dosages for Herpes Simplex Labialis, Herpes Simplex - Suppression, Herpes … Each gram of Acyclovir Ointment USP, 5% contains 50 mg of acyclovir in a polyethylene glycol (PEG) base.Acyclovir is a white, crystalline powder with the molecular formula CThe chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; it has the following structural formula:The inhibitory activity of acyclovir is highly selective due to its affinity for the enzyme thymidine kinase (TK) encoded by HSV and VZV. Carcinogenesis, Mutagenesis, Impairment of Fertility:To report SUSPECTED ADVERSE REACTIONS, contact Camber Pharmaceuticals, Inc. at 1-866-495-1995 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatchTherapy should be initiated as early as possible following onset of signs and symptoms. Acyclovir Ointment Dosage and Administration. Select one or more newsletters to continue. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. Therefore, systemic absorption of acyclovir after topical application is minimal.In clinical trials of initial genital herpes infections, Acyclovir Ointment USP, 5% has shown a decrease in healing time and, in some cases, a decrease in duration of viral shedding and duration of pain. Detailed Acyclovir dosage information for adults and children. This is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase. Local pruritus occurred in 4% of these patients. If you are a consumer or patient please visit A finger cot or rubber glove should be used when applying Acyclovir to prevent autoinoculation of other body sites and transmission of infection to other persons. Acyclovir excreted in the urine ranged from <0.02% to 9.4% of the daily dose.
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