alogliptin dose tastylia

Select one or more newsletters to continue. Applies to the following strengths: 12.5 mg-15 mg; 12.5 mg-30 mg; 12.5 mg-45 mg; 25 mg-15 mg; 25 mg-30 mg; 25 mg-45 mgMild renal dysfunction (CrCl greater than or equal to 60 mL/min): No adjustment recommended.For patients with congestive heart failure (NYHA Class I or II):Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Take a missed dose as soon as you think about it. 122, 201, 202. Maximal PD effects were observed at the 10 mg kg − 1 dose in these animals. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for ALOGLIPTIN. Alogliptin tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [see Clinical Studies (14)].Important Limitations of UseAlogliptin tablets are not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, as it would not be effective in these settings. Total body clearance: 14 L/hr If you have problems with your kidneys, your doctor might give you a lower dose of 12.5mg or 6.25mg a … Do not take 2 doses at the same time or extra doses. Available for Android and iOS devices. Alogliptin comes as 25mg, 12.5mg or 6.25mg tablets. Individualize the initial dose based on patients current regimen Initial dose: alogliptin 12.5 mg-metformin 500 mg OR alogliptin 12.5 mg-metformin 1000 mg orally twice a day Maintenance dose: Adjust dose based on efficacy and tolerability Maximum dose: alogliptin 25 mg-metformin 2000 mg per day Comments: -When used in combination with insulin or insulin secretagogues such as sulfonylureas, a lower dose of insulin or the insulin secretagogue may be required to minimize the risk of hypoglycemia.
What do I do if I miss a dose? Alogliptin dose-dependently inhibited plasma DPP-4 activity, increased GLP-1 levels, augmented early-phase insulin secretion, and reduced blood glucose excursion in response to an oral glucose challenge. We comply with the HONcode standard for trustworthy health information - The usual dose is 25mg a day. Renal clearance: 9.6 L/hr. Usual dose: 25 mg orally once a day Comments: When used in combination with insulin or insulin secretagogues such as sulfonylureas, a lower dose of insulin or the insulin secretagogue may be required to minimize the risk of hypoglycemia.

Available for Android and iOS devices. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Select one or more newsletters to continue. Alogliptin / pioglitazone systemic 25 mg / 15 mg (A/P 25/15) Keep taking alogliptin as you have been told by your doctor or other health care provider, even if you feel well. Applies to the following strengths: 6.25 mg; 12.5 mg; 25 mgMild Renal Impairment (CrCl 60 mL/min or greater): No adjustment recommendedMild to moderate liver dysfunction (Child-Pugh Grade A and B): No adjustment recommendedIf used in combination with insulin or an insulin secretagogue such as sulfonylureas, a lower dose of insulin or the insulin secretagogue may be required to minimize the risk of hypoglycemia.Safety and efficacy have not been established in patients younger than 18 years.Hemodialysis: 6.25 mg orally once a day; may be administered without regard to the timing of dialysisAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Elimination. Individualize dose based on current regimen and concurrent medical condition: For patients inadequately controlled on diet and exercise or metformin monotherapy: -Initial dose: alogliptin-pioglitazone 25 mg/15 mg or 25 mg/30 mg orally once a day -For patients on alogliptin requiring additional glycemic control: -Initial dose: alogliptin-pioglitazone 25 mg/15 mg or 25 mg/30 mg orally once a day For patients on pioglitazone requiring additional glycemic control: -Initial dose: alogliptin-pioglitazone 25 mg/15 mg, 25 … Does not undergo extensive metabolism and 60-71% of the dose is excreted unchanged in the urine. We comply with the HONcode standard for trustworthy health information -

Usual Adult Dose for Diabetes Type 2.

Half-life: 21 hr. Greater sensitivity of some geriatric individuals to alogliptin cannot be ruled out, particularly if the geriatric patient has co-existing cardiac or kidney disease, which may increase the risk for heart failure in some geriatric patients.

Active metabolite: N-demethylated (1% of parent compound) Inactive metabolite: N-acetylated alogliptin (6% of parent compound) Minor substrate of CYP3A4 and CYP2D6. Dose adjustment based on renal function may be needed. …

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