alternatives to amiodarone for vt aygestin
A double‐blind randomised trialA double‐blind trial of metoprolol in acute myocardial infarction. I have been told by electrophysiologist,after he failed to address the problem. Nonetheless, amiodarone is approved for use against VT and VF by most regulatory agencies worldwide and has a high profile as a useful drug. The cardiac arrhythmia suppression trialRelation of mortality to failure to prescribe beta blockers acutely in patients with sustained ventricular tachycardia and ventricular fibrillation following acute myocardial infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry)Amiodarone interaction with beta‐blockers: analysis of the merged EMIAT (European Myocardial Infarct Amiodarone Trial) and CAMIAT (Canadian Amiodarone Myocardial Infarction Trial) databases. During long-term management of patients on amiodarone, routine toxicity screening is required. These trials indicate increased cardiovascular mortality from several class I drugsAmiodarone may result in serious noncardiac toxicity, particularly pulmonary infiltrates, hepatic dysfunction, thyroid dysfunction, and peripheral neuropathy. IV Lidocaine is an alternative treatment for recurrent sustained VT not responding to Beta‐blockers or Amiodarone and is recommended as such in current ESC guidance. with an ablation,that I should stop taking Amiodarone 200mg. This includes periodic (usually every 6 months) measurement of thyroid (sensitive serum T4), hepatic (AST), and pulmonary function (chest x-ray), as well as clinical evaluation.Amiodarone is currently the leading antiarrhythmic drug because of proven efficacy and safety. Nonetheless, 3 decades of clinical experience worldwide and a clear-cut reduction in arrhythmic death in the randomized placebo-controlled prophylactic trials provide somewhat indirect but convincing evidence that amiodarone is effective against VT/VF recurrence, although the degree of benefit remains imprecise. Ventricular arrhythmias occur commonly following myocardial infarction and carry important prognostic implications. Treatment of Stable Patients is based on Arrhythmia Type: Ventricular Tachycardia: Procainamide (Pronestyl) 30 mg/min IV, up to a total max of 17 mg/kg, or Amiodarone (Cordarone) 150-300 mg IV over 10-20 min, or Lidocaine 0.75 mg/kg. Please re-ask & clarify. Pharmacological therapy remains the major approach to management of AF, and use of amiodarone is likely to increase in future years.Reprint requests to Stuart J. Connolly, MD, Hamilton Health Sciences Corporation, Hamilton General Site, 237 Barton St E, Hamilton, ON L8L 2X2, Canada. Thanks are due to Dr John A. Cairns, University of British Columbia, and Professor Michael Gent, McMaster University, for their helpful criticism of the manuscript. The “leading circle” concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obstacleRegional changes in blood flow, extracellular potassium and conduction during myocardial ischemia and reperfusionAlterations in repolarization of cardiac Purkinje fibers recovering from ischemic‐like conditions: genesis of early afterdepolarizationsBasic mechanisms of cardiac impulse propagation and associated arrhythmiasRole of gap junctions in the propagation of the cardiac action potentialCardiac ischemia and uncoupling: gap junctions in ischemia and infarctionReentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlationMagnitude and prognosis associated with ventricular arrhythmias in patients hospitalized with acute coronary syndromes (from the GRACE Registry)The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarctionIncidence, determinants, and prognostic value of reverse left ventricular remodelling after primary percutaneous coronary intervention: results of the Acute Myocardial Infarction Contrast Imaging (AMICI) multicenter studyRandomized trial of preventive angioplasty in myocardial infarction2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC)endorsed by: association for European Paediatric and Congenital Cardiology (AEPC)Effect on mortality of metoprolol in acute myocardial infarction.
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