american academy of pediatrics breastfeeding drug list minipress

Hale TW. Stowe ZN. Wisner KL, Clinical points to remember about choosing medications in breastfeeding mothers: Breastfeeding is important and even temporary disruption can affect milk supply. Breastfeeding and human milk are the normative standards for infant feeding and nutrition. You may be trying to access this site from a secured browser on the server. Trusted answers from the American Academy of Pediatrics. Slusser W. Retrograde diffusion of the drug from breast milk to plasma may remove a medication from the milk even if the mother has not emptied her breasts.In the early postpartum period, large gaps between the mammary alveolar cells allow many medications to pass through this milk that may not be able to enter mature milk. St. Louis: Mosby, 1999Information from Hale TW. Use topical therapy when possible since serum levels are usually very small.Transfer of medication from the maternal serum into milk depends on the drug’s oral availability, lipid solubility, molecular weight, protein binding and half life. The American Academy of Pediatrics works diligently to ensure that health professionals are educated about breastfeeding and able to support breastfeeding families. Cohen LS, Physicians receive little education about breast-feeding and even less training on the effects of maternal medications on the nursing infant.The mammary tissue in the breast is composed of clusters of milk-producing alveolar cells surrounding a central lumen. Visit AAP News on Facebook ; Follow AAP News on Twitter; Marijuana and Breast Milk . According to the AAP, its use is compatible with breastfeeding although it may cause decreased milk production.Inhaled steroids for the treatment of asthma achieve very low levels in maternal plasma and are of no concern for the breastfeeding mother.

Sources of funding: none reportedFreed GL, Cefalo R, Medications and mothers' milk: 1999–2000.8th ed. The transfer of drugs and other chemicals into human milk. Advising a breastfeeding mother on the compatibility of her medications and breastfeeding can often be a source of confusion. Clark SJ, Although diltiazem (Cardizem CD) is rated compatible with breast-feeding by the AAP, the levels found in breast milk are higher than the levels for other calcium channel blockers, so safer alternatives are preferred.Insulin is not excreted into breast milk and is considered safe for use during breast-feeding.The alpha-glucosidase inhibitors, such as acarbose (Precose), have low bioavailability, large molecular size and water solubility, so they are unlikely to be excreted into breast milk in clinically significant amounts.Because of the potential for serious side effects (e.g., lactic acidosis, hepatotoxicity) in adults, it may be advisable to avoid the use of metformin (Glucophage) and thiazolidinediones (e.g., rosiglitazone [Avandia], pioglitazone [Actos]) until more information is available on their use in breast-feeding.Although anticonvulsants are excreted into breast milk, most mothers who require the use of these drugs can safely breast-feed their infants.Phenytoin (Dilantin) and carbamazepine (Tegretol) are compatible with breast-feeding.During breast-feeding, anticonvulsants other than phenobarbital and primidone (Mysoline) are preferred because the slow rate of barbiturate metabolism by the infant may cause sedation.Penicillins and cephalosporins, which are excreted in milk in trace amounts, are compatible with breast-feeding.Tetracycline is excreted in small amounts in breast milk, but the calcium in breast milk limits its absorption. “Compatible” is a better word since it acknowledges a risk-benefit balance. Briggs GG, Freeman RK, Yaffe SJ. Principles of drug transfer into breast milk and drug disposition in the nursing infant. View the collection. This clinical report covers diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants (both breastfed and formula fed) and toddlers from birth through 3 years of age. . Curtis P. Please turn on JavaScript and try again. Oral steroids such as prednisone (Deltasone) and prednisolone (Delta-Cortef) penetrate into the breast milk poorly and are safe for short-term use. Rubin AP.

Breastfeeding: a guide for the medical profession. Breastfeeding Position Paper, American Academy of Family Physicians A paper explaining the American Academy of Family Physicians' stance on breastfeeding. Advice to pump and discard milk assumes that the mother can afford or has a breast pump, that she knows how to use that pump, and that her baby will know how to take a bottle.A drug must reach the maternal serum in order to penetrate into milk.

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