aminophylline iv cordarone

does not need to be protected from light during administration. Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. Tachykarde Arrhythmien >

Severe toxicity may occur without preceding milder symptoms (see also 4.9 Overdose).Hypersensitivity reactions (see also Skin and subcutaneous tissue disorders).Metabolic disturbances such as hypokalaemia, hypophosphataemia, and hyponatraemia may occur.Headache, insomnia, confusion, restlessness, hyperventilation, anxiety, vertigo/dizziness, tremor. In clinical studies of 2 to 7 days, clearance of amiodarone after intravenous administration in patients with VT and VF ranged between 220 and 440 mL/h/kg. Avvertenze, Interazioni Farmacologiche, Effetti Indesiderati e Controindicazioni. Subsequently, the approximate IV aminophylline maintenance doses described above may be considered.Aminophylline injection should not be used in patients hypersensitive to ethylenediamine or those allergic to the theophyllines, caffeine or theobromine. Cordarone I.V. Theophylline clearance may be increased in smokers and in those regularly exposed to tobacco smoke.During regular therapy serum potassium levels must be monitored. ), schwere respiratorische Insuffizienz (Inj. It has stimulant effect on respiration, and also a diuretic action of short duration. liver, lungs) [Package Insert- Pacerone(R)], therefore, if an individual was taking amiodarone on a chronic basis, if it is stopped it will remain in the system for weeks to months. The incidence of severe side effects in this group is low. In December 1985, amiodarone was approved by the FDA for the treatment of arrhythmias.Amiodarone is available in oral and intravenous formulations.

Patients whose arrhythmias have been suppressed by Cordarone I.V. A range of 5 to 15 mcg/ml may be effective, and associated with fewer adverse effects.The dosage should be titrated for each individual and adjusted with caution. IF ANY NEW SIGNS OF ARRHYTHMIA APPEAR, THE POSSIBILITY OF HYPERTHYROIDISM SHOULD BE CONSIDERED (see Cordarone I.V. Effects of an inadvertent overdose of Cordarone I.V. may cause a worsening of existing arrhythmias or precipitate a new The need to co-administer amiodarone with any other drug known to prolong the QTc interval must be based on a careful assessment of the potential risks and benefits of doing so for each patient. Torsades de pointes auslösenden Medikamenten, verlängertes QT-Intervall, Kreislaufkollaps, schwere Hypotonie, Hypokaliämie, Schilddrüsenfunktionsstörungen, MAO-Hemmer-Therapie, Hypotonie (Inj. It allows continued monitoring of the benefit/risk balance of the medicinal product. IV Aminophylline should be the first line IV therapy in patients with COPD, whereas IV aminophylline or IV salbutamol can be used for patients with asthma if they are not responding to standard treatment. When therapeutic doses of Aminophylline and/or theophylline are administered simultaneously by more that one route or in more than one preparation, the hazard of serious toxicity is increased. IN CONTROLLED AND Other treatment-emergent possibly drug-related adverse events reported in less than 2% of patients receiving Cordarone I.V. Aminophylline has a narrow therapeutic index, therefore cautious dosage determination is essential. must be delivered by a volumetric infusion pump. When suggestions are available use up and down arrows to review and ENTER to select. Amiodarone HCl has the following structural formula: Amiodarone HCl is a white to slightly yellow crystalline powder, … Since grapefruit juice is known to inhibit CYP3A4-mediated The following table provides suggested doses of oral Cordarone to be initiated after varying durations of Cordarone I.V. They … Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.Aminophylline has a narrow therapeutic index. Although the safe use of theophylline during pregnancy has not been established relative to potential risk to the foetus, theophyllines have been used during pregnancy without teratogenicity or other adverse foetal effect. Aminophylline relaxes smooth muscle and relieves bronchial spasm. Coma may develop in very severe cases.Palpitations, arrhythmias, hypotension, supraventricular and ventricular arrhythmias may occur. INFUSION * Cordarone I.V. It is used both in supraventricular arrhythmias and ventricular arrhythmias. Repeated oral administration of activated charcoal enhances the elimination of theophylline from the body even after intravenous administration. Therapeutic serum concentrations of theophylline are considered to range from 10 to 20 mcg/ml and levels greater than 20 mcg/ml are often associated with toxic effects. Accumulation of amiodarone and DEA occurs in adipose tissue and highly perfused organs (i.e. Cordarone I.V. Amiodarone IV is a known vesicant. A Cosa Serve? Intravenous aminophylline can be used for acute exacerbation of symptoms and reversible airway obstruction in asthma and other chronic lung disease such as COPD, emphysema and chronic bronchitis. Cordarone Intravenous (Cordarone I.V.)

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