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This products label may have been revised after this insert was used in production. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. A new warning for DRESS has been added to Geodon product labeling. The review concluded that SGLT2 inhibitors may increase the risk of diabetic ketoacidosis in patients using these medications for treatment of type 2 diabetes. Health Canada has recommended that the manufacturers of sevoflurane products strengthen the existing product safety information to include the evidence reported in published studies about this risk. Health care providers should consider the diagnosis of pancreatitis in patients taking Blincyto who experience severe upper abdominal pain accompanied by nausea, vomiting, or abdominal tenderness. Health care providers should discontinue prescribing Zecuity, and patients should stop using any remaining patches and contact their prescribers for an alternative migraine medicine.The vaccine strains approved for the 2016-2017 season in the United States are as follows: Trivalent influenza vaccines will contain an A/California/7/2009 (H1N1)pdm09-like virus, an A/Hong Kong/4801/2014 (H3N2)-like virus, and a B/Brisbane/60/2008-like virus (B/Victoria lineage). There are currently 2 lots of Antivenin (Micrurus fulvius) (Equine Origin) available for use including lot number 4030024 and lot number 4030026, with an expiration date of October 31, 2014.Institutions should retain any remaining inventory of either lot number 4030024 or 4030026 until the aforementioned expiration dates. The mold was found to be present as a contaminant in an unopened container of the ABC Dophilus Powder, which is formulated to contain 3 species of live bacteria.The FDA advises health care providers to use dietary supplements containing live bacteria or yeast in immunocompromised patients with caution. The FDA is monitoring and evaluating this safety issue and will work with manufacturers regarding any future label changes that would address the risk of severe hypersensitivity reactions.Before using a topical OTC acne drug product for the first time, consumers should apply a small amount to 1 or 2 small affected areas for 3 days to make sure they do not develop hypersensitivity symptoms.The FDA has completed its safety review of olmesartan and has found no clear evidence of increased cardiovascular risks associated with olmesartan in diabetic patients. Health Canada’s review concluded that there is a link between sevoflurane and the risk of bradycardia in children with Down syndrome. For patients with suspected or documented toxoplasmosis who do not have a history of sulfa allergy, trimethoprim-sulfamethoxazole should be used in place of pyrimethamine-containing regimens until pyrimethamine is available.The FDA has strengthened the warning for the type 2 diabetes medicines Invokana and Invokamet (canagliflozin) related to the increased risk of bone fractures, and added new information about decreased bone mineral density to the product labeling. With the updated dosing recommendations, patients with early, chronic phase CML who have been taking nilotinib for 3 years or more, and who achieved and maintained a molecular response to treatment, may be eligible to stop taking nilotinib. The risk of these cardiac events, including abnormal heart rhythms, may also be increased when high doses of loperamide are taken with other medications that interact with loperamide. However, the FDA issued a Complete Response Letter to Genzyme in December 2013, indicating Lemtrada is not ready for approval. Health Canada is currently working with manufacturers to update product labels for lithium to include new warnings regarding the risk of hypercalcemia and hyperparathyroidism, as well as the need to consider calcium monitoring before initiating lithium, after 6 months on therapy, and annually during long-term therapy.The FDA is investigating the risk of stroke, heart attack, and death in men taking FDA-approved testosterone products. for life-threatening VT/VF; it was not dose-related. Effects of an inadvertent overdose of Cordarone I.V. However, in a study in which amiodarone HCl was orally administered to male and female rats, beginning 9 weeks prior to mating, reduced fertility was observed at a dose level of 90 mg/kg/day (approximately 1.4 times the maximum recommended human maintenance dose*). Assess kidney function prior to starting canagliflozin or dapagliflozin and monitor periodically thereafter. Failure to properly reconstitute the concentrate vial with the entire amount of diluent may lead to a higher dosage of Jevtana being administered and increased risk of toxicity (eg, bone marrow suppression, gastrointestinal effects). In the event licensed antivenin cannot be secured, an investigational imported antivenin may be available under an Investigational New Drug (IND) protocol with informed consent; for more information contact a local Poison Control Center at 800-222-1222 or the U.S. Food and Drug Administration (FDA) at 800-835-4709 (business hours) or 301-796-8240 (nonbusiness hours).Amgen Canada Inc, and Health Canada are informing health care professionals of the risk of capillary leak syndrome (CLS) associated with the use of granulocyte colony stimulating factors For additional information, please refer to the following:Sanofi withdrew its leukemia therapy Campath (alemtuzumab) from the U.S. market in September 2012 to prepare for a relaunch (under the name Lemtrada) at a lower dose to treat relapsing-remitting multiple sclerosis (MS).

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