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In patients already receiving Levodopa the dosage of this drug may gradually be decreased, while the dosage of BROMOCRIPTINE is increased until the optimum balance is determined.Prescribing of BROMOCRIPTINE in children and adolescents (aged 7-17) should be limited to Paediatric Endocrinologists.There is no clinical evidence that BROMOCRIPTINE poses a special risk to the elderly.In patients with impaired hepatic function, the speed of elimination may be retarded and plasma levels may increase, requiring dose adjustment.Hypersensitivity to bromocriptine or to any of the excipients of BROMOCRIPTINE (see Section 2 Qualitative and Quantitative composition and 6.1 List of excipients) or other ergot alkaloids. There is insufficient evidence of efficacy of BROMOCRIPTINE in the treatment of premenstrual symptoms and benign breast disease. Based on the outcome of more than 2,000 pregnancies, the use of BROMOCRIPTINE to restore fertility has not been associated with an increased risk of abortion, premature delivery, multiple pregnancy or malformation in infants. Monitoring of visual fields in patients with macroprolactinoma is therefore recommended for an early recognition of secondary field loss due to chiasmal herniation and adaptation of drug dosage.In some patients with prolactin-secreting adenomas treated with BROMOCRIPTINE, cerebrospinal fluid rhinorrhea has been observed. Kopitar Z, Vrhovac B, Povsic L, Plavsić F, Francetić I, Urbancic J.Eur J Drug Metab Pharmacokinet. In these patients, treatment with BROMOCRIPTINE often results in tumour shrinkage and rapid improvement of the visual fields defects. Sudden onset of sleep during daily activities, in some cases without awareness or warning signs, has been reported very rarely. Dosage may then be increased by 2.5mg at 2 to 3 day intervals as follows: - 2.5mg eight-hourly, 2.5mg six-hourly, 5mg six-hourly.Introduce BROMOCRIPTINE gradually, as follows: Week 1: 1mg to 1.25mg at bed time. BROMOCRIPTINE is not recommended for the routine suppression of lactation or for the relief of symptoms of post-partum pain and engorgement which can be adequately treated with non-pharmacological intervention (such as firm breast support, ice application) and/or simple analgesics.The treatment of hyperprolactinaemia in men and women with hypogonadism and/or galactorrhoea.Amenorrhoea and oligomenorrhoea, with or without galactorrhoea.Some infertile women with oligomenorrhoea or amenorrhoea and galactorrhoea may be unduly sensitive to prolactin.

Uncommon: Fatigue.

Pharmacotherapeutic group: Dopamine agonist (ATC code N04B C01), prolactin inhibitor (ATC code G02C B01)BROMOCRIPTINE, active ingredient bromocriptine, is an inhibitor of prolactin secretion and a stimulator of dopamine receptors. Vomiting, somnolence and fever were reported as adverse events. BROMOCRIPTINE has been used successfully in the treatment of a number of infertile women with galactorrhoea who do not have demonstrable hyperprolactinaemia.To reduce tumour size, particularly in those at risk of optic nerve compression.BROMOCRIPTINE has been used in a number of specialised units, as an adjunct to surgery and/or radiotherapy to reduce circulating growth hormone in the management of acromegalic patients.In the treatment of idiopathic Parkinson's Disease, BROMOCRIPTINE has been used both alone and in combination with Levodopa in the management of previously untreated patients and those disabled by 'on-off' phenomena. As a precautionary measure, patients should be monitored to detect signs of pituitary enlargement so that BROMOCRIPTINE may be reintroduced if necessary. Background: Although there are clinical reports of hair loss associated with levodopa and dopamine agonists, it is unclear whether dopamine exerts any direct effects on the human hair follicle (HF). Furthermore, a reduction of dosage or termination of therapy may be considered.When women of child-bearing age are treated with BROMOCRIPTINE for conditions not associated with hyperprolactinaemia the lowest effective dose should be used.

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