classification of antiviral drugs according to mechanism of action mysoline

It differs from ACV in having a single hydroxymethyl group in the acyclic side chain. Anti viral drugs mean the agent that works against viral infection.It has majorly 4 classes of drugs, so for that watch the video. The interferon when given with ribavirin has proved to be more effective than interferon alone for treatment of hepatitis C virus infection. After administration, the drug is available in more quantity and persists for a longer time in infected cells than ACV.The penciclovir also has some antiviral activity against cytomegalovirus and Epstein–Barr virus.Ganciclovir is a guanine nucleoside, chemically related to ACV. Antiviral Drugs – A Brief (Classification & Mechanism of Actions) 1. They are potent inhibitors of the influenza neuraminidase. Interferons exert antiviral effect by several pathways as follows:They cause increased expression of class I and class II MHC (major histocompatibility complex) glycoproteins, thereby facilitating the recognition of viral antigens by immune system.They activate the cells, such as natural killer cells and macrophages, the cells with the ability to destroy virus-infected targets.Interferons are now being increasingly used for treatment of chronic hepatitis B and C virus carriers who are at risk to progress to cirrhosis and hepatocellular carcinoma. Foscarnet specifically inhibits DNA polymerase of all herpes viruses and reverse transcriptase of the HIV. Classification of Antiviral Drugs The antiviral agents available against viruses can be classified as: (a) nucleoside analogs, (b) non-nucleoside polymerase inhibitors, (c) protease inhibi-tors, (d) neuraminidase inhibitors, (e) M2 channel blockers, and (f) interferons. This regimen should be continued until satisfactory dosage level is achieved for the combination, or the other medication is completely withdrawn. See our These compounds inhibit the enzyme reverse transcriptase by preventing DNA chain elongation. See our Currently, synthetic IFN- is actively used against hepatitis A, B, and C viruses; papilloma virus; HSV; and rhinovirus. In several clinical trials, both the agents have demonstrated efficacy with minimal side effects. This prevents multiplication and thus restricts the spread of infection. Pregnant women under anticonvulsant therapy should receive prophylactic vitamin K1 therapy for 1 month prior to, and during, delivery.The total daily dosage should not exceed 2 g. Since Mysoline therapy generally extends over prolonged periods, a complete blood count and a sequential multiple analysis-12 (SMA-12) test should be made every 6 months.There is evidence in mothers treated with primidone that the drug appears in breast milk in substantial quantities. These agents act by inhibiting HIV replication by blocking the enzyme reverse transcriptase. If required, an increase to five or six 250 mg tablets daily may be made, but daily doses should not exceed 500 mg four times a day.Dosage should be individualized to provide maximum benefit. Have u ever tried external professional writing services like ⇒ www.WritePaper.info ⇐ ? It acts mainly by preventing replication of the viruses by inhibiting nucleoside biosynthesis, mRNA capping, and other processes essential for viral replication.When administered as an aerosol, ribavirin has been shown to be effective for treatment of severe respiratory syncytial viral infection in children and for treatment of severe influ-enza and measles in adults.Intravenous ribavirin is also effective for treatment of infections caused by influenza B virus and Rift Valley virus, and Lassa, Crimean-Congo, and other hemorrhagic fevers.Ribavirin in combination with interferon-alpha (IFN-) is shown to be effective against the infection caused by hepa-titis C virus.Dideoxynucleosides (e.g., dideoxyinosine, dideoxycytidine, stavudine, and lamivudine), the analogs of nucleosides, have been synthesized for use against HIV.

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