clindamycin phosphate gel uses toprol xl
should be made whether to discontinue nursing or to discontinue the drug,
vehicle-controlled, parallel comparison clinical trial in which patients used Clindagel®
a history of hypersensitivity to preparations containing In an open label, parallel group study of 24 patients
the treatment of acne vulgaris.
Clindamycin Hydrochloride phosphate and tretinoin gel 1.2% / 0.025% is indicated for the topical treatment of acne vulgaris in patients 12 years or older. than the human dose of clindamycin phosphate from 5 milliliters of Clindagel®
Clindamycin phosphate gel USP, 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram.Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.The gel contains allantoin, carbomer 974P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water.The mechanism of action of clindamycin in treating acne vulgaris is unknown.Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. , assuming complete absorption and based on a A 1% clindamycin phosphate gel similar to Clindagel®
skin where acne lesions appear. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.Studies indicate a toxin(s) produced by clostridia is one primary cause of antibiotic-associated colitis. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface.
agents are more appropriate. by: DPT Laboratories, Ltd., San Antonio, Texas
Do not
sunlight.Genotoxicity tests performed included a rat micronucleus
In Summary. in a study in hairless mice in which tumors were induced by exposure to simulated
Therefore, it should be used with caution in patients receiving such agents.In clinical trials with pregnant women, the systemic administration of clindamycin during the second and third trimesters has not been associated with an increased frequency of congenital abnormalities. However, orally and parenterally
milk following use of Clindagel®. Tito chatoyant discredits his freckles anyway. benzoyl peroxide gel: clindamycin phosphate gel clindamycin phosphate sol: differin cream differin gel : differin lotion erythromycin gel: erythromycin solution erythromycin-benzoyl perox.
Clindamycin: Uses & Side Effects.
See below for a comprehensive list of adverse effects. test and an Ames Salmonella reversion test. Large bowel endoscopy should be considered to establish a definitive diagnosis in cases of severe diarrhea.Antiperistaltic agents such as opiates and diphenoxylate with atropine may prolong and/or worsen the condition. If angina markedly worsens or acute coronary insufficiency develops, Along with its needed effects, metoprolol (the active ingredient contained in Some side effects of metoprolol may occur that usually Check with your health care professional if any of the following side effects The most common adverse reactions were tiredness, dizziness, 1. Clindamycin phosphate topical gel, 1% is a topical antibioticapproved for the treatment of acne vulgaris. (including Clindagel® should be prescribed with caution in
Use enough to cover the entire affected area
This article provides an overview of clindamycin, including what it can treat, how much doctors recommend taking, and possible adverse effects and interactions.
diarrhea and pseudomembranous colitis, the physician should consider whether other
gel: tretinoin cream tretinoin gel: preferred donepezil
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Cerner Multum, Inc. "Australian Product Information." hydrochloride and clindamycin palmitate hydrochloride. gel, 1%, a topical The chemical name for clindamycin phosphate is methyl
In view of the potential for diarrhea, bloody
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(clindamycin phosphate topical gel, 1%) once daily or the vehicle gel once
O 02. sufficient numbers of patients aged 65 and over to determine if they respond
There are no adequate studies in pregnant women during the first trimester of pregnancy. Endoscopic examination may reveal pseudomembranous colitis. "Product Information. LLC, Bridgewater, NJ 08807 USA. daily, in the treatment of acne vulgaris of mild to moderate severity, There was a trend in the investigator's global assessment
clindamycin palmitate hydrochloride have revealed no evidence of impaired
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