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Martin A: Acute pancreatitis associated with clozapine use [Letter]. Helwick CA: Review of clozapine therapy finds more ADRs than expected. Recently admitted antipsychotic drugs also have systemic side effects. Thompson J, Chengappa KN, Good CB, Baker RW, Kiewe RP, Bezner J, Schooler NR: Hepatitis, hyperglycemia, pleural effesion, eosinophilia, hematuria and proteinuria occurring early in clozapine treatment. Wirshing WC, Phelan CK, Van Putten T, Marder SR, Engel J: Effects of clozapine on treatment-resistant akathisia and concomitant tardive dyskinesia [Letter]. Schoretsanitis, Georgios : Single vs multiple-dose pharmacokinetics of clozapine in psychiatric patients. Alvir JM, Lieberman JA: Agranulocytosis: Incidence and risk factors. All rights reserved. Clozapine use is frequently associated with: 3, 10. 2019. Cohen BM, Keck PE, Satlin A, Cole JO: Prevalence and severity of akathisia in patients on clozapine. Sections. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Wilkinson, Emma L. Khalil N: Peri/myocarditis with clozapine (leponex). ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Liukkonen J, Koponen HJ, Nousiainen U: Clinical picture and long-term course of epileptic seizures that occur during clozapine treatment. 20,21,34 However, several recent studies … Goldring, Christopher E. Gerson SL: G-CSF and the management of clozapine induced agranulocytosis. Fenton WS, Blyler CF, Heinssen PK: Determinants of medication compliance in schizophrenia: Empirical and clinical findings. George TP, Sernyak MJ, Ziedonis DM, Woods SW: Effects of clozapine on smoking in chronic schizophrenic outpatients. Sison-Young, Rowena L. These side effects may go away during treatment as your body adjusts to the medicine. Over 10 million scientific documents at your fingertips Karagianis JL, Phillips LC, Hogan KP, LeDrew KK: Clozapine-associated neuroleptic malignant syndrome: Two new cases and a review of the literature. Rechlin T, Claus D, Weis M: Heart rate variability in schizophrenic patients and changes of autonomic heart rate parameters during treatment with clozapine. All rights reserved. Young CR, Bowers, MB, Jr., Mazure CM: Management of the adverse effects of clozapine. Bartell PJ, Donenwirth K, et al. Rädisch, Steffen A problem in the treatment of schizophrenia is poor patient compliance leading to the recurrence of psychotic symptoms. Safferman AZ, Lieberman JA, Pollack S, Kane JM: Akathisia and clozapine treatment [Letter]. Robinson D, Fenn H, Yesavage J: Possible association of parotitis with clozapine. Bambina, E. Hayes G, Gibler B: Clozapine-induced constipation [Letter]. Lieberman JA: Maximizing clozapine therapy: Managing side effects. Cerner Multum, Inc. "UK Summary of Product Characteristics." Cerner Multum, Inc. "Australian Product Information." [Letter]. 3. It has been proven effective and significantly superior to placebo, as well as to conventional neuroleptics, in several placebo-controlled, double-blind studies in treatment-resistant schizophrenia. Schuster P, Gabriel E, Kufferle B, Strobl G, Karobath M: Reversal by physostigmine of clozapine-induced delirium. de Leon, Jose Vasile JS, Steingard S: Clozapine and the development of salivary gland swelling: A case study. Goldring, Christopher E. Wetterling T: Body weight gain with atypical antipsychotics—A comparative review. : Clinical evaluation and effective usage of dantrolente sodium in neuroleptic malignant syndrome. Sign up now. Meltzer HR, Matsubara S, Lee JC: Classification of typical and atypical antipsychotic drugs on the basis of D1-D2 and serotonin, PK1 values. Kugler J, Lorenzi E, Spatz R, et al. Since weight gain and obesity are associated with increased rates of diabetes and lipid abnormalities in the general population, it is not surprising that atypical antipsychotics have been shown to increase glucose and lipid levels. Lieberman JA, Kane JM, and Johns CA: Clozapine: Guidelines for clinical management. Leadbetter R, Shutty M, Pavalonis D, Vieeg V, Higgins P, Downs M: Clozapine-induced weight gain: Prevalence and clinical relevance. Rice DP, Miller LS: The economic burden of schizophernia. Sachdev P, Kurk J, Kneebone M, Kissane D: Clozapine-induced neuroleptic malignant syndrome: Review and report of new cases. Department of Psychiatry, State University of New York, Upstate Medical University, Syracuse, New YorkDepartment of Neurology, School of Medicine, The University of Alabama at Birmingham, Birmingham, AlabamaDepartment of Psychiatry and Behavioral Neurobiology, School of Medicine, The University of Alabama at Birmingham, Birmingham, AlabamaZahid Husain, Syed Zaber Mahmud, William G. Ryan & Jacqueline M. FeldmanYou can also search for this author in

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