cyclophosphamide injection adalat

Cyclophosphamide appears to induce its own metabolism. The elimination half-life (tTotal body clearance (CL) of cyclophosphamide is decreased by 40% in patients with severe hepatic impairment and elimination half-life (tCyclophosphamide was mutagenic and clastogenic in multiple Cyclophosphamide is genotoxic in male and female germ cells. Your doctor may occasionally change your dose. The pharmacokinetics of cyclophosphamide were determined following one-hour intravenous infusion to renally impaired patients. Based on mechanism of action and published reports of effects in pregnant patients or animals, drug can cause fetal harm when administered to pregnant woman; exposure to cyclophosphamide during pregnancy may cause fetal malformations, miscarriage, fetal growth retardation, and toxic effects in the newborn; drug is teratogenic and embryo-fetal toxic in mice, rats, … Follow special handling and disposal proceduresCyclophosphamide Injection, 500 mg/2.5 mL Vial LabelCyclophosphamide Injection, 500 mg/2.5 mL Carton Label This interaction may result in an increased incidence of graft-versus-host disease.Depolarizing muscle relaxants: Cyclophosphamide treatment causes a marked and persistent inhibition of cholinesterase activity. The sterile powder formulation contains NLT 90.0% and NMT 105.0% of the labeled amount of anhydrous cyclophosphamide (C 7 H 15 Cl 2 N 2 O 2 P). What is nifedipine? Antimycotics and/or antivirals may also be indicated.Monitoring of complete blood counts is essential during cyclophosphamide treatment so that the dose can be adjusted, if needed. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Cyclophosphamide for injection is an alkylating drug indicated for treatment of: • Malignant Diseases: malignant lymphomas: Hodgkin's disease, lymphocytic lymphoma, mixed-cell type lymphoma, histiocytic lymphoma, Burkitt's lymphoma; multiple myeloma, leukemias, mycosis fungoides, neuroblastoma, adenocarcinoma of ovary, retinoblastoma, breast carcinoma. H‰\”Íjã0F÷~ Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Fever without documented infection has been reported in neutropenic patients.Nausea and vomiting occur with cyclophosphamide therapy. Gently swirl the vial to dissolve the drug completely. Adalat CC tablets consist of an external coat and an internal core. Brand Names: Adalat, Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL Generic Name: nifedipine. Causal association is unclear. 10 to 20% is excreted unchanged in the urine and 4% is excreted in the bile following IV administration. Cyclosporine injection is used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person receiving the organ) in people who have received kidney, liver, and heart transplants. Other intravenous regimens include 10 mg per kg to 15 mg per kg given every 7 to 10 days or 3 mg per kg to 5 mg per kg twice weekly.When cyclophosphamide is included in combined cytotoxic regimens, it may be necessary to reduce the dose of cyclophosphamide as well as that of the other drugs.Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.Cyclophosphamide does not contain any antimicrobial preservative and thus care must be taken to assure the sterility of prepared solutions. Talk to your doctor about the risks of using this medication for your condition. Cyclophosphamide is an alkylating drug indicated for treatment of: Cyclophosphamide Injection: 200 mg/mL (500 mg/2.5 mL and 1 g/5 mL) in a multiple-dose vial (Adverse reactions reported most often include neutropenia, febrile neutropenia, fever, alopecia, nausea, vomiting, and diarrhea. In case of neutropenic fever, antibiotic therapy is indicated. Follow all directions on your prescription label and read all medication guides or instruction sheets. ©!ŞäFo×ö0¶Ñó›1ä1Û6|ÒYQ›üXmë­�á($šõ©ï=Ñ“t2Ñ¥Î±Ê m“&iÔ~b[�_Çİğ6¦-ÈŞ¤j�­Jå `A¡sCÓ2l¹`¶ZÌtŞQB•©j?uY }ìëÔ³R#Ş‹e‰4Té#Túmtë†X¤Òó´ieX±Á´ÔX”;ÈåO¸Ø"˜�^îK¬àtmÒlÛM¢KcYÅE©÷Ğ_¿­)èû ı04ô³á�Æ×~Nâe\|¢1y}¸«ÔØÅPÿ²ÖğÿŸµFw;©ü7x¢¦µ†ãlQ“çî§&w75m‚¹{®!„æ—âéj‘¶zY×$m c(Â�ÊíZ†¯­ùfÓÎqStt¿ÍØ�ò¦iãKMÔ—uÍZgOIc¤y¹÷FB£�é¬ù:û7’"§?ş` ÖÜ Skin rash occurs occasionally in patients receiving the drug.

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