cyproheptadine liquid dosage aldactone

4 mg PO q8hr initially; maintenance: 4-20 mg/day, up to 32 mg/day divided q8hr in some patients; not to exceed 0.5 mg/kg/day 4-12 mg PO 1-2 hours before anticipated coitus or 1-16 mg/day12 mg initially PO, followed by 2 mg q2hr or 4-8 mg PO q6hr as needed to control symptomsNonanticholinergic antihistamines should be considered first when treating allergic reactions (Beers Criteria)Advanced age is associated with reduced clearance and greater risk of confusion, dry mouth, constipation, and other anticholinergic effects and toxicity; use lower end of dosage range (4 mg PO q12hr) for elderly patients, or administer less frequentlyRenal impairment: Elimination is reduced in renal insufficiency; administer lower doses, and monitor closely2-6 years old: 2 mg PO q8-12hr; not to exceed 12 mg/day7-14 years old: 4 mg PO q8-12hr; not to exceed 16 mg/dayAlternatively, total daily dose of 0.25 mg/kg or 8 mg/m²>3 years and adolescents: 0.2-0.4 mg/kg/day PO divided BID; not to exceed 0.5 mg/kg/day>13 years: 2 mg PO q6hr initially; increased to up to 8 mg q6hr over 3 weeksRenal impairment: Elimination is reduced in renal insufficiency; administer lower doses, and monitor closelyPsychiatric/neurologic: CNS depression, drowsiness, sedation ranging from mild drowsiness to deep sleep (most frequent), dizziness, lassitude, disturbed coordination; less commonly, restlessness, insomnia, tremors, euphoria, nervousness, irritability, delirium, seizures, toxic psychosis, paresthesiaCardiovascular: Palpitation, tachycardia, palpitation, ECG changes (eg, widened QRS), arrhythmias (eg, extrasystole, heart block), hypotension, hypertension, dizziness, sedation, hypotensionGI: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipationHepatic: Cholestasis, hepatitis, hepatic failure, hepatic function abnormality, jaundice (rare)Skin: Eczema, pruritus, inflammation, papular rash, erythema on exposed skinSensory: Visual disturbances, blurred vision, diplopia, tinnitus, acute labyrinthitisRespiratory: Thickening of bronchial secretions, wheezing, nasal stuffinessOther: Vertigo, sweating, chills, early menses, headache, impotence, dryness of mouth, nose, and throat, facial dyskinesia, tightness of chest, faintnessUse with caution in cardiovascular disease, including hypertensionElderly patients: Avoid use in elderly because of high incidence of anticholinergic effects; may exacerbate existing lower urinary conditions or benign prostatic hyperplasia; if used, administer at low end of dosage rangeMay cause CNS depression, which may impair mental abilities; use caution when operating heavy machineryUse caution in cardiovascular disease, including hypertension and ischemic heart diseaseUse with caution in patients with increased intraocular pressure, history of asthma or other chornic breathing disorders, or thyroid dysfunctionNonanticholinergic antihistamines should be considered first for treatment of allergic reaction in the elderly (Beers criteria)Antihistamines may cause excitation in young childrenLactation: Excretion in milk unknown; contraindicatedA: Generally acceptable. Usual Adult Dose for Urticaria 2010 https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvY3lwcm9oZXB0YWRpbmUtMzQzMzg5 Decreased Appetite Secondary to Chronic Disease (Off-label) 2 mg PO q6hr for one week; THEN 4 mg PO q6hr Drug-Induced Sexual Dysfunction (Off-label) 4 … 2001 Since cyproheptadine is primarily metabolized by the liver, caution is advised when it is administered to patients with impaired hepatic function.Cyproheptadine should not be used in newborn or premature infants.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Controlled studies in pregnant women show no evidence of fetal risk.Serotonin and histamine antagonist; competitively inhibits H1 receptor, mediating bronchial constriction, smooth-muscle contraction, edema, hypotension, CNS depression, and cardiac arrhythmias; prevents histamine release in blood vessels and is more effective in preventing histamine response than in reversing it; may be useful in patients with syndromes sustained by histamine-producing tumorsModerate anticholinergic activity with low sedative effectMetabolites: Quaternary ammonium glucuronide conjugateAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. Initial dose: 4 mg orally three times a day Maintenance dose: 12 to 16 mg/day, occasionally up to 32 mg/day but not to exceed 0.5 mg/kg/day. Please confirm that you would like to log out of Medscape. 2002 The therapeutic range is 4 to 20 mg a day, with the majority of patients requiring 12 to 16 mg a day.

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