diflucan 50mg capsules

adverse effects, nor should it be construed to indicate Fluconazole is also a strong inhibitor of the isozyme CYP2C19. Fluconazole has been shown to be more selective for fungal cytochrome P-450 enzymes than for various mammalian cytochrome P-450 enzyme systems. Other ingredients Capsules (50 mg, 100 mg, 150 mg and 200 mg capsules): gelatin, lactose, maize starch, silicon dioxide, magnesium stearate, sodium lauryl sulfate, titanium dioxide, (50, 100 and 150 mg capsules only), patent blue V. Up to 28 days. A dose of 100, 200 and 400 mg in adults corresponds to a 3, 6 and 12 mg/kg dose in children to obtain a comparable systemic exposure. • Mucosal candidiasis including oropharyngeal, oesophageal candidiasis, candiduria and chronic mucocutaneous candidiasis. Capsules contain lactose monohydrate. A higher fluconazole plasma elimination half-life of approximately 24 hours was found after a single dose. For children, dosage is also based on This medication works best when the amount of medicine in your body is kept at a constant level. Fluconazole is largely excreted in the urine; forced volume diuresis would probably increase the elimination rate. Longer periods may be used in patients with severely compromised immune function.

Capsules contain lactose and should not be given to patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. If a rash, which is considered attributable to fluconazole, develops in a patient treated for a superficial fungal infection, further therapy with this medicinal product should be discontinued. Discard any unused Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

The distribution volume in this age group was about 950 ml/kg. Studies in animals have shown reproductive toxicity (see section 5.3).Fluconazole in standard doses and short-term treatments should not be used in pregnancy unless clearly necessary.

Additional data were available from a compassionate use study. Treatment should start several days before the anticipated onset of neutropenia and continue for 7 days after recovery from neutropenia after the neutrophil count rises above 1000 cells per mmDosage should be adjusted based on the renal function (see “Fluconazole capsule is predominantly excreted in the urine as unchanged active substance.

Fluconazole clearance is proportional to creatinine clearance. Fluconazole hepatotoxicity has usually been reversible on discontinuation of therapy. The onset of parturition was slightly delayed at 20 mg/kg orally and dystocia and prolongation of parturition were observed in a few dams at 20 mg/kg and 40 mg/kg intravenously.

Do not use a kitchen teaspoon, as this will not give you the right amount. • To reduce the incidence of recurrent vaginal candidiasis (4 or more episodes a year). Diflucan 50mg Capsules 28 Drug Name: fluconazole Product ID: 2488386. Do not store above 25°C.

They are for use only for organisms that do not have specific breakpoints. Fluconazole capsule has been associated with rare cases of serious hepatic toxicity including fatalities, primarily in patients with serious underlying medical conditions. Such a hormone change has not been observed in women treated with fluconazole (see section 5.1). Fluconazole capsule treated patients who are concomitantly treated with medicinal products with a narrow therapeutic window metabolised through CYP2C9, CYP2C19 and CYP3A4, should be monitored (see section 4.5). Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.Interaction studies have shown that when oral fluconazole is coadministered with food, cimetidine, antacids or following total body irradiation for bone marrow transplantation, no clinically significant impairment of fluconazole absorption occurs Fluconazole is a moderate inhibitor of cytochrome P450 (CYP) isoenzymes 2C9 3A4. Plasma concentrations are proportional to dose.

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