ethambutol drug interactions lipitor

Interaction of Ethambutol with human organic cation transporters of the SLC22 family indicates potential for drug-drug interactions during antituberculosis therapy Antimicrob Agents Chemother. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ethambutol hydrochloride is an oral chemotherapeutic agent which is specifically effective against actively growing microorganisms of the genus Mycobacterium, including M. tuberculosis. The effects of some drugs can change if you take other drugs or herbal products at the same time. These medications may cause some risk when taken together. It is believed to work by preventing the bacteria from continuing to grow. General Instructions. 2013 Oct;57(10):5053-9. doi: 10.1128/AAC.01255-13. These drug interactions are possible, but do not always occur. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:This is not a complete list of possible side effects.

This information is not individual medical advice and does not substitute for the advice of your health care professional. No drug accumulation has been observed with consecutive single daily doses of 25 mg/kg in patients with normal kidney function, although marked accumulation has been demonstrated in patients with renal insufficiency.Ethambutol hydrochloride diffuses into actively growing Ethambutol hydrochloride has been shown to be effective against strains of Toxicological studies in dogs on high prolonged doses produced evidence of myocardial damage and failure, and depigmentation of the tapetum lucidum of the eyes, the significance of which is not known. These drug interactions are possible, but do not always occur. Testing the visual acuity through a pinhole eliminates retractive error. DDI analysis indicated a strong potential for ethambutol interaction on hOCT1 expressed in enterocytes and hepatocytes and on hOCT3 in enterocytes, which would alter absorption, distribution, and excretion of coadministered cationic drugs, suggesting that in vivo pharmacokinetic studies are necessary to confirm drug safety and efficacy. Film coating and polishing contains: hydroxypropyl methylcellulose, polyethylene glycol, polysorbate 80, and titanium dioxide.Ethambutol hydrochloride following a single oral dose of 25 mg/kg of body weight, attains a peak of 2 to 5 mcg/mL in serum 2 to 4 hours after administration. 4 When the drug is administered daily for longer periods of time at this dose, serum levels are similar. Description Simple . Copyright(c) 2013 First Databank, Inc.Mycobacterium tuberculosis is the bacterium that causes tuberculosis (TB). Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.Selected from data included with permission and copyrighted by First Databank, Inc.

Symptoms and signs of TB include bloody sputum, fever, cough, weight loss, and chest pain. Moderate Interactions. MAC, is a mycobacteria that causes lung infections and disease. Please turn on JavaScript and try again. Degenerative changes in the central nervous system, apparently not dose-related, have also been noted in dogs receiving Ethambutol hydrochloride over a prolonged period. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. In fetuses born of mice treated with high doses of Ethambutol hydrochloride during pregnancy, a low incidence of cleft palate, exencephaly and abnormality of the vertebral column were observed.

Take your next dose at the regular time. Antacids. This medication may sometimes be taken twice weekly.

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