ezetimibe contraindications robaxin

Ezetimibe tablets do not help you lose weight. Take in the evening. Fibric Acid Derivatives may increase the serum concentration of Ezetimibe.Teriflunomide: May increase the serum concentration of OATP1B1/1B3 (SLCO1B1/1B3) Substrates.Tolvaptan: May increase the serum concentration of OATP1B1/1B3 (SLCO1B1/1B3) Substrates. Ezetimibe should not be used in nursing mothers unless the potential benefit justifies the potential risk to the infant.The effects of Ezetimibe coadministered with simvastatin (n=126) compared to simvastatin monotherapy (n=122) have been evaluated in adolescent boys and girls with heterozygous familial hypercholesterolemia (HeFH). After completing the 12-week study, eligible patients were assigned to Ezetimibe coadministered with fenofibrate or fenofibrate monotherapy for an additional 48 weeks.Ezetimibe coadministered with fenofibrate significantly lowered total-C, LDL-C, Apo B, and non-HDL-C compared to fenofibrate administered alone. In a multicenter, double-blind, controlled study followed by an open-label phase, 142 boys and 106 postmenarchal girls, 10 to 17 years of age (mean age 14.2 years, 43% females, 82% Caucasians, 4% Asian, 2% Blacks, 13% multi-racial) with HeFH were randomized to receive either Ezetimibe coadministered with simvastatin or simvastatin monotherapy. Administration of Ezetimibe with a statin is effective in improving serum total-C, LDL-C, Apo B, non-HDL-C, TG, and HDL-C beyond either treatment alone. The empirical formula is C Ezetimibe is a white, crystalline powder that is freely to very soluble in ethanol, methanol, and acetone and practically insoluble in water. Use is contraindicated in pregnant women who require combination therapy with an HMG-CoA reductase inhibitor. In a 2-week clinical study in 18 hypercholesterolemic patients, Ezetimibe inhibited intestinal cholesterol absorption by 54%, compared with placebo. Read all information given to you. Cyclosporine concentrations should be monitored in patients receiving Ezetimibe and cyclosporine.The degree of increase in Ezetimibe exposure may be greater in patients with severe renal insufficiency. Do not take 2 doses at the same time or extra doses. Fenofibrate and Derivatives may increase the serum concentration of Ezetimibe.Fibric Acid Derivatives: May enhance the adverse/toxic effect of Ezetimibe. Drug therapy is indicated as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other non-pharmacologic measures alone has been inadequate.Ezetimibe tablets, administered alone, are indicated as adjunctive therapy to diet for the reduction of elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and non-high-density lipoprotein cholesterol (non-HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia.Ezetimibe tablets, administered in combination with a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor (statin), is indicated as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary (heterozygous familial and non-familial) hyperlipidemia.Ezetimibe tablets administered in combination with fenofibrate, are indicated as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, Apo B, and non-HDL-C in adult patients with mixed hyperlipidemia.The combination of Ezetimibe tablets and atorvastatin or simvastatin is indicated for the reduction of elevated total-C and LDL-C levels in patients with HoFH, as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable.Ezetimibe tablets are indicated as adjunctive therapy to diet for the reduction of elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia.The effect of Ezetimibe tablets on cardiovascular morbidity and mortality has not been determined.Ezetimibe tablets have not been studied in Fredrickson Type I, III, IV, and V dyslipidemias.The recommended dose of Ezetimibe tablets is 10 mg once daily.Ezetimibe tablets can be administered with or without food.Ezetimibe tablets may be administered with a statin (in patients with primary hyperlipidemia) or with fenofibrate (in patients with mixed hyperlipidemia) for incremental effect.

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