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Diseases & Conditions 1 g IV/IM; additional doses at q8hr until PO; not to exceed 3 g/dayTotal parenteral dose SHOULD NOT EXCEED 3 g/day for >3 days, unless treating tetanus; if condition persists, may repeat therapy after drug-free interval of 48 hr1500 mg PO q6hr for 48-72 hours; not to exceed 8 g/day THEN decrease to 4-4.5 g/day divided q4-8hrAdjunct therapy: Initial 1-2 g IV injection (at 300 mg/min), THENAdditional 1-2 g IV infusion for total dose of 3 g initiallyRenal failure: Not studied; parenteral dosage form contraindicated due to presence of polyethylene glycol15 mg/kg/dose IV q6hr PRN or 500 mg/m²/dose; not to exceed 1.8 g/m²/day for 3 days only >16 years: 1500 mg PO q6hr for 48-72 hours; not to exceed 8 g/day THEN decrease to 4-4.5 g/day divided q4-8hr Considered safe in elderly because of short half-life500 mg PO q6hr; may gradually titrate dose to responseMay cause drowsiness/dizziness; patients should not ingest alcohol or other CNS depressantsIV formulation not for use in renal impairment (contains polyethylene glycol; injection rate should not exceed 3 mL/minMay interfere with screening tests for 5-HIAA and vanillylmandelic acid (VMA)Use injection with caution in patients with a history of seizuresSedative effects potentiated when used with other sedativesLactation: Not known if excreted in breast milk; use cautionA: Generally acceptable.
Do not use it later for another condition unless your doctor directs you to do so. informational and educational purposes only. Please confirm that you would like to log out of Medscape. Your list will be saved and can be edited at any time.The above information is provided for general Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
Diseases & Conditions https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvcm9iYXhpbi1tZXRob2NhcmJhbW9sLTM0MzM0Mw== The dosage is based on your medical condition and response to treatment.Tell your doctor if your condition does not improve or if it worsens.Tell your doctor right away if you have any serious side effects, including: This is not a complete list of possible side effects.

Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. You may report side effects to Health Canada at 1-866-234-2345.This drug may make you dizzy or drowsy or blur your Older adults may be more sensitive to the side effects of this drug, especially confusion, Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as If someone has overdosed and has serious symptoms such as passing out or This medication has been prescribed for your current condition only.



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