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Of the most frequently reported (>1%) side effects, rash, vomiting, and diarrhea occurred in greater proportions of older patients. A dosage of 400 mg once daily may be used, based on medical judgment of the patient's response to therapy. Adjustment of dosage of NSAIDs may be needed.Moderate inhibitors of CYP3A4 such as Fluconazole increase olaparib plasma concentrations; concomitant use is not recommended. An oral dose of 7.5 mg of midazolam was ingested after Fluconazole/placebo. In post-marketing experience, as with other azole antifungals, bleeding events (bruising, epistaxis, gastrointestinal bleeding, hematuria, and melena) have been reported in association with increases in prothrombin time in patients receiving Fluconazole concurrently with warfarin. A dosage of 12 mg/kg once daily may be used, based on medical judgment of the patient's response to therapy. Ten of these patients were concomitantly receiving diuretics. ScienceDirect ® is a registered trademark of Elsevier B.V.URL: https://www.sciencedirect.com/science/article/pii/B9780444537171007526URL: https://www.sciencedirect.com/science/article/pii/B9780323244855002655URL: https://www.sciencedirect.com/science/article/pii/S1075628001270050URL: https://www.sciencedirect.com/science/article/pii/S0378608010320277URL: https://www.sciencedirect.com/science/article/pii/B9780702062858001568URL: https://www.sciencedirect.com/science/article/pii/B9781416056805000086URL: https://www.sciencedirect.com/science/article/pii/B9781416056805000074URL: https://www.sciencedirect.com/science/article/pii/B978141602882650037XURL: https://www.sciencedirect.com/science/article/pii/B9780443067075500511URL: https://www.sciencedirect.com/science/article/pii/B978012373944500331XMeyler's Side Effects of Drugs (Sixteenth Edition), 2016Saunders Handbook of Veterinary Drugs (Fourth Edition)Analytical Profiles of Drug Substances and ExcipientsScienceDirect ® is a registered trademark of Elsevier B.V.

You can take Fluconazole at any time of the day.Fluconazole keeps working for several days to treat the infection. A published survey of 96 breastfeeding women who were treated with Fluconazole 150 mg every other day (average of 7.3 capsules [range 1 to 29 capsules]) for lactation-associated candida of the breasts reported no serious adverse reactions in infants. This effect on midazolam appears to be more pronounced following oral administration of Fluconazole than with Fluconazole administered intravenously. The metabolite, GZDV, to parent drug ratio significantly decreased after the administration of Fluconazole, from 7.6 ± 3.6 to 5.7 ± 2.2.The pharmacokinetics of theophylline were determined from a single intravenous dose of aminophylline (6 mg/kg) before and after the oral administration of Fluconazole 200 mg daily for 14 days in 16 normal male volunteers. In the study, subjects ingested placebo or 400 mg Fluconazole on Day 1 followed by 200 mg daily from Day 2 to Day 6. Fluconazole enhanced the blood pressure-lowering effects of nifedipine by increasing its plasma concentrations in a 16-year-old man with malignant pheochromocytoma taking chronic nifedipine for arterial hypertension who was given fluconazole for Candida septicemia [112].The mass spectrum of fluconazole reported in the Wiley Registry of Mass Spectral Data Itraconazole therapy of invasive candidiasis has not been adequately evaluated. Similar proportions of older patients (2.4%) and younger patients (1.5%) discontinued Fluconazole therapy because of side effects. (See Fluconazole increases the serum concentrations of theophylline. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. The combined use of Fluconazole with cisapride is contraindicated. Fluconazole, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration and as a powder for oral suspension.Fluconazole is designated chemically as 2,4-difluoro-α,αFluconazole is a white crystalline solid which is slightly soluble in water and saline.Fluconazole Tablets contain 50 mg, 100 mg, 150 mg, or 200 mg of Fluconazole and the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C Red No. Terfenadine acid metabolite AUC increased 36% ± 36% (range: 7 to 102%) from Day 8 to Day 15 with the concomitant administration of Fluconazole. (See The effects of Fluconazole on the pharmacokinetics of the sulfonylurea oral hypoglycemic agents tolbutamide, glipizide, and glyburide were evaluated in three placebo-controlled studies in normal volunteers.

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