\u00a9 2020 wikiHow, Inc. All rights reserved. They were more commonly observed during the treatment of chronic diarrhea.The adverse events reported are summarized irrespective of the causality assessment of the investigators.1) Adverse events from 4 placebo-controlled studies in patients with acute diarrhea The adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride, were: dry mouth, flatulence, abdominal cramp and colic.2) Adverse events from 20 placebo-controlled studies in patients with chronic diarrheaThe adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented below in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride were: nausea, vomiting, headache, meteorism, abdominal pain, abdominal cramp and 3) Adverse events from seventy-six controlled and uncontrolled studies in patients with acute or chronic diarrheaThe adverse events with an incidence of 1.0% or greater in patients from all studies are given in the table below.Isolated occurrences of allergic reactions and in some cases severe hypersensitivity reactions including A number of the adverse events reported during the clinical investigations and post- marketing experience with loperamide are frequent symptoms of the underlying diarrheal syndrome (abdominal pain/discomfort, nausea, vomiting, dry mouth, tiredness, drowsiness, dizziness, constipation, and flatulence).
(approximately 21 times the human dose based on a body surface area comparison) produced impairment of male fertility, whereas administration of up to 10 mg/kg/day (approximately 5 times the human dose based on a body surface area comparison) had no effect.Teratology studies have been performed in rats using oral doses of 2.5, 10, and 40 mg/kg/day, and in rabbits using oral doses of 5, 20, and 40 mg/kg/day. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Your intestines don’t absorb the normal amounts of nutrients and fluids. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Increases the transit time of stoolthrough the colon.
\u00a9 2020 wikiHow, Inc. All rights reserved. They were more commonly observed during the treatment of chronic diarrhea.The adverse events reported are summarized irrespective of the causality assessment of the investigators.1) Adverse events from 4 placebo-controlled studies in patients with acute diarrhea The adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride, were: dry mouth, flatulence, abdominal cramp and colic.2) Adverse events from 20 placebo-controlled studies in patients with chronic diarrheaThe adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented below in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride were: nausea, vomiting, headache, meteorism, abdominal pain, abdominal cramp and 3) Adverse events from seventy-six controlled and uncontrolled studies in patients with acute or chronic diarrheaThe adverse events with an incidence of 1.0% or greater in patients from all studies are given in the table below.Isolated occurrences of allergic reactions and in some cases severe hypersensitivity reactions including A number of the adverse events reported during the clinical investigations and post- marketing experience with loperamide are frequent symptoms of the underlying diarrheal syndrome (abdominal pain/discomfort, nausea, vomiting, dry mouth, tiredness, drowsiness, dizziness, constipation, and flatulence).
(approximately 21 times the human dose based on a body surface area comparison) produced impairment of male fertility, whereas administration of up to 10 mg/kg/day (approximately 5 times the human dose based on a body surface area comparison) had no effect.Teratology studies have been performed in rats using oral doses of 2.5, 10, and 40 mg/kg/day, and in rabbits using oral doses of 5, 20, and 40 mg/kg/day. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Your intestines don’t absorb the normal amounts of nutrients and fluids. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Increases the transit time of stoolthrough the colon.
\u00a9 2020 wikiHow, Inc. All rights reserved. They were more commonly observed during the treatment of chronic diarrhea.The adverse events reported are summarized irrespective of the causality assessment of the investigators.1) Adverse events from 4 placebo-controlled studies in patients with acute diarrhea The adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride, were: dry mouth, flatulence, abdominal cramp and colic.2) Adverse events from 20 placebo-controlled studies in patients with chronic diarrheaThe adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented below in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride were: nausea, vomiting, headache, meteorism, abdominal pain, abdominal cramp and 3) Adverse events from seventy-six controlled and uncontrolled studies in patients with acute or chronic diarrheaThe adverse events with an incidence of 1.0% or greater in patients from all studies are given in the table below.Isolated occurrences of allergic reactions and in some cases severe hypersensitivity reactions including A number of the adverse events reported during the clinical investigations and post- marketing experience with loperamide are frequent symptoms of the underlying diarrheal syndrome (abdominal pain/discomfort, nausea, vomiting, dry mouth, tiredness, drowsiness, dizziness, constipation, and flatulence).
(approximately 21 times the human dose based on a body surface area comparison) produced impairment of male fertility, whereas administration of up to 10 mg/kg/day (approximately 5 times the human dose based on a body surface area comparison) had no effect.Teratology studies have been performed in rats using oral doses of 2.5, 10, and 40 mg/kg/day, and in rabbits using oral doses of 5, 20, and 40 mg/kg/day. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Your intestines don’t absorb the normal amounts of nutrients and fluids. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Increases the transit time of stoolthrough the colon.
These symptoms are often difficult to distinguish from undesirable drug effects.A specific clinical study designed to assess the abuse potential of loperamide at high doses resulted in a finding of extremely low abuse potential.Nonclinical data have shown that loperamide is a P-When a single 16-mg dose of loperamide is coadministered with a 600 mg single dose of saquinavir, loperamide decreased saquinavir exposure by 54%, which may be of clinical relevance due to reduction of therapeutic efficacy of saquinavir. This image may not be used by other entities without the express written consent of wikiHow, Inc. \n<\/p>
\u00a9 2020 wikiHow, Inc. All rights reserved. They were more commonly observed during the treatment of chronic diarrhea.The adverse events reported are summarized irrespective of the causality assessment of the investigators.1) Adverse events from 4 placebo-controlled studies in patients with acute diarrhea The adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride, were: dry mouth, flatulence, abdominal cramp and colic.2) Adverse events from 20 placebo-controlled studies in patients with chronic diarrheaThe adverse events with an incidence of 1.0% or greater, which were reported at least as often in patients on loperamide hydrochloride as on placebo, are presented below in the table below.The adverse events with an incidence of 1.0% or greater, which were more frequently reported in patients on placebo than on loperamide hydrochloride were: nausea, vomiting, headache, meteorism, abdominal pain, abdominal cramp and 3) Adverse events from seventy-six controlled and uncontrolled studies in patients with acute or chronic diarrheaThe adverse events with an incidence of 1.0% or greater in patients from all studies are given in the table below.Isolated occurrences of allergic reactions and in some cases severe hypersensitivity reactions including A number of the adverse events reported during the clinical investigations and post- marketing experience with loperamide are frequent symptoms of the underlying diarrheal syndrome (abdominal pain/discomfort, nausea, vomiting, dry mouth, tiredness, drowsiness, dizziness, constipation, and flatulence).
(approximately 21 times the human dose based on a body surface area comparison) produced impairment of male fertility, whereas administration of up to 10 mg/kg/day (approximately 5 times the human dose based on a body surface area comparison) had no effect.Teratology studies have been performed in rats using oral doses of 2.5, 10, and 40 mg/kg/day, and in rabbits using oral doses of 5, 20, and 40 mg/kg/day. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Your intestines don’t absorb the normal amounts of nutrients and fluids. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. This image is not<\/b> licensed under the Creative Commons license applied to text content and some other images posted to the wikiHow website. Increases the transit time of stoolthrough the colon.
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