iv bactrim dose

… Total daily dose is 8 to 10 mg/kg (based on the trimethoprim component) given in 2 or 4 equally divided doses every 6, 8 or 12 hours for up to 14 days for severe urinary tract infections and 5 days for shigellosis. Bactrim contains a combination of sulfamethoxazole and Bactrim is used to treat ear infections, urinary tract infections, bronchitis, Bactrim may also be used for purposes not listed in this medication guide.You should not take sulfamethoxazole and trimethoprim if you are pregnant or breastfeeding.You should not use Bactrim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:kidney disease that is not being treated or monitored;anemia (low red blood cells) caused by folic acid deficiency;a history of low blood platelets after taking trimethoprim or any sulfa drug; orTo make sure Bactrim is safe for you, tell your doctor if you have:Take Bactrim exactly as prescribed by your doctor.

Bactrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.Some epidemiologic studies suggest that exposure to sulfamethoxazole/trimethoprim during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot. PCP: 15-20mg/kg/day in 3 or 4 divided doses.

You may report side effects to FDA at 1-800-FDA-1088.You may need more frequent check- ups or medical tests if you also use medicine to treat Many drugs can interact, and some drugs should not be used together. 1052279-overview

Available for Android and iOS devices. Patients with renal dysfunction, liver disease, malnutrition or those receiving high doses of Bactrim are particularly at risk.Trimethoprim has been noted to impair phenylalanine metabolism, but this is of no significance in phenylketonuric patients on appropriate dietary restriction.As with all drugs containing sulfonamides, caution is advisable in patients with porphyria or thyroid dysfunction.Co-administration of Bactrim and leucovorin should be avoided with High dosage of trimethoprim, as used in patients with Severe and symptomatic hyponatremia can occur in patients receiving Bactrim, particularly for the treatment of During treatment, adequate fluid intake and urinary output should be ensured to prevent crystalluria.

Individual plans may vary

Rapid infusion or bolus injection must be avoided.

Usual Adult Dose for Urinary Tract Infection.

For the lower limit dose (75 mg/kg sulfamethoxazole and 15 mg/kg trimethoprim per 24 hours) administer 75% of the dose in the above table. Pharmacology, adverse reactions, warnings and side effects.

The maximum recommended daily dose is 60 mL per day.

In some rabbit studies, an overall increase in fetal loss (dead and resorbed conceptuses) was associated with doses of trimethoprim 6 times the human therapeutic dose based on body surface area.There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, possible folate deficiency, or concomitant use of other drugs.

Available for Android and iOS devices. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Bactrim, given at a common clinical dosage, increased the phenytoin half-life by 39% and decreased the phenytoin metabolic clearance rate by 27%. Version: 9.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Adults: The usual adult dosage in the treatment of urinary tract infections is 1 BACTRIM DS (double strength) tablet or 2 BACTRIM tablets every 12 hours for 10 to 14 days. Dosage Forms Discontinued in US [oral susp, IV not avail. Cases of interactions with other OCT2 substrates, memantine and metformin, have also been reported.In the literature, three cases of hyperkalemia in elderly patients have been reported after concomitant intake of sulfamethoxazole/trimethoprim and an angiotensin converting enzyme inhibitor.The presence of sulfamethoxazole and trimethoprim may also interfere with the Jaffé alkaline picrate reaction assay for creatinine, resulting in overestimations of about 10% in the range of normal values.While there are no large, well-controlled studies on the use of sulfamethoxazole and trimethoprim in pregnant women, Brumfitt and Pursell,Because sulfamethoxazole and trimethoprim may interfere with folic acid metabolism, Bactrim should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.While there are no large prospective, well controlled studies in pregnant women and their babies, some retrospective epidemiologic studies suggest an association between first trimester exposure to sulfamethoxazole/trimethoprim with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot.

Single 820-mg dose: 27.5 to 31.7 mcg/mL. Sulfamethoxazole is an inhibitor of CYP2C9. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Lange on bactrim iv dose: It will be pretty much gone a day or two after your last dose.

Lastly, outcome measures varied between studies, limiting cross-study comparisons. Tell your doctor about all your current medicines, especially:an "ACE inhibitor" heart or blood presure medication (This list is not complete and many other drugs may interact with sulfamethoxazole and trimethoprim.

Select one or more newsletters to continue. In two studies in rats, no teratology was observed when 512 mg/kg of sulfamethoxazole was used in combination with 128 mg/kg of trimethoprim.

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