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summarized in Table 12.To evaluate the safety and efficacy of the higher dose and shorter course of LEVAQUINClinical success rates (cure plus improvement) in the clinically evaluable population were 90.9% in the 500 mg oral dose of LEVAQUINThe pharmacokinetics of levofloxacin following a single 7 mg/kg intravenous dose were investigated in On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age. Levofloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) Levofloxacin may also be used for purposes not listed in this medication guide.Levofloxacin can cause serious side effects, including tendon problems, nerve damage, serious mood or behavior changes, or You should not use this medicine if you are allergic to levofloxacin or other fluoroquinolones (tendon problems, bone problems, arthritis or other joint problems (especially in children);blood circulation problems, aneurysm, narrowing or hardening of the arteries;a genetic disease such as Marfan syndrome or Ehler's-Danlos syndrome;Do not give this medicine to a child without medical advice.It is not known whether this medicine will harm an unborn baby. Levofloxacin can cause serious side effects, including tendon problems, side effects on your nerves (which may cause permanent nerve damage), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).low blood sugar--headache, hunger, sweating, irritability, nerve symptoms in your hands, arms, legs, or feet--numbness, weakness, tingling, burning pain;serious mood or behavior changes--nervousness, confusion, agitation, paranoia, hallucinations, memory problems, trouble concentrating, thoughts of suicide; orsigns of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions).severe stomach pain, diarrhea that is watery or bloody;fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);the first sign of any skin rash, no matter how mild;increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; orliver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, This is not a complete list of side effects and others may occur. LEVAQUIN. This MDRSP isolates are isolates resistant to two or more of the following antibacterials: penicillin (MIC ≥2 Subsequent pharmacokinetic analyses predicted that a dosage regimen of 8 mg/kg every 12 hours (not to As with other fluoroquinolones, disturbances of blood glucose, including symptomatic hyper- and Stop taking LEVAQUIN at LEVAQUINIf CDAD is suspected or confirmed, ongoing antibiotic use not directed against In immature rats and dogs, the oral and intravenous administration of levofloxacin resulted in increased

extent of exposure (AUC) to that observed for LEVAQUINThe mean volume of distribution of levofloxacin generally ranges from 74 to 112 L after single and after oral LEVAQUINPatients should be informed that if they are diabetic and are being treated with insulin or an oral common.LEVAQUIN may cause false-positive urine screening results for opiates when testing is done with pharmacist when you get a new medicine.Taking all of your LEVAQUIN doses will help make sure that all of the bacteria are killed. You may report side effects to FDA at 1-800-FDA-1088.The data demonstrate that from pH 0.6 to 5.8, the solubility of levofloxacin is essentially constant (approximately 100 mg/mL). concentrations are usually attained one to two hours after oral dosing. creatinine clearance less than 50 mL/min, adjustments to the dosing regimen are required [see In patients with renal impairment (creatinine clearance less than 50 mL/min), adjustment of the dosage

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