lidocaine dose for ventricular tachycardia diabecon

Lidocaine is administered as an IV bolus of 75 to 100 mg (1.5 mg/kg). Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Information, resources, and support needed to approach rotations - and life as a resident.Valuable tools for building a rewarding career in health care.Information and tools for librarians about site license offerings.The authorized source of trusted medical research and education for the Chinese-language medical community.The most trusted, influential source of new medical knowledge and clinical best practices in the world.Effect of Lidocaine on Ventricular Arrhythmias in Patients with Coronary Heart Disease Lidocaine is rarely indicated in cats, because clinically significant or life-threatening ventricular arrhythmias are rare in this species. Lidocaine is considered a second-line antiarrhythmic drug and should be administered in VF/VT cases where amiodarone is either unavailable or ineffective. The dosage in cats is 0.1–0.4 mg/kg, IV bolus over ~1 min, then increase to a total dose of 0.25–1 mg/kg, IV slowly, if no response. informational and educational purposes only. May repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total if refractory VF or pulseless VTContinuous infusion: 1-4 mg/min IV after return of perfusionAdminister 0.5 mg/kg bolus and reassess infusion if arrhythmia reappears during constant infusionEndotracheal (loading dose): 2-3.75 mg/kg (2 to 2.5 recommended IV dose); dilute in 5-10 mL 0.9% saline or sterile water1-1.5 mg/kg; repeat doses of 0.5-0.75 mg/kg in 5-10 minutes up to 3 mg/kg total; follow with 1-4 mg/min continuous infusionAcute management of ventricular arrhythmias (cardiac surgery, acute MI)Off-label: Peds with premature ventricular beats during cardiac arrestIM dose indicated when IV admin is not possible or when ECG monitoring is not available and danger of ventricular arrhythmia is greatBolus: 0.5-1 mg/kg IV/IO/ET, not to exceed 100 mg; follow with continuous infusion; if delay between bolus and start of infusion is >15 minutes, administer a second bolus q5-10min to 5 mg/kg, THENHypersensitivity to lidocaine or amide-type local anestheticAdams-Stokes syndrome, SA/AV/intraventricular heart block in the absence of artificial pacemakerCHF, cardiogenic shock, 2nd and 3rd degree heart block (if no pacemaker is present), Wolff-Parkinson-White SyndromeConstant monitoring with an EKG is essential to the proper administration of lidocaine IV; discontinue immediately with signs of excessive depression of cardiac conductivity (eg, PR interval prolongation, QRS interval widening, arrhythmia exacerbation)If malignant hyperthermia develops, discontinue administration immediately and institute therapeutic countermeasures as clinically indicatedLidocaine hydrochloride should not be added to blood transfusion assemblies because of possibilities of pseudoagglutination or hemolysisNot recommended as prophylaxis in acute MI (controversial)Liver disease, CHF, bradycardia, Wolff-Parkinson-White syndrome, marked hypoxia, severe respiratory depression, hypovolemia, incomplete heart blockUse extreme caution in patients with severe hepatic impairment; may increase risk of lidocaine toxicityRisk of lidocaine toxicity may increase in patients with pseudocholinesterase deficiencyGood for automatic and re-entrant arrhythmias, not PSVTsReproduction studies have been performed in rats at doses up to five times maximum human dose and have revealed no significant findings; however, no adequate and well-controlled studies in pregnant women available; physicians should carefully consider potential risks and benefits for each specific patient before prescribing lidocaine hydrochloride; may cross the placental barrierPresent in human milk; published studies have reported a range of lidocaine milk: plasma ratios between 0.4-1.1; limited data available on lidocaine’s effects on breastfed child have not revealed consistent pattern of associated adverse events; development and health benefits of breastfeeding should be considered along with mother’s clinical need for lidocaine and potential adverse effects on breastfed infant from lidocaine or from underlying maternal conditionA: Generally acceptable.

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