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In view of the dose-dependent adverse reactions, treatment with doses above 300 mg/day is not recommended The recommended dose of LYRICA is 75 to 150 mg two times a day, or 50 to 100 mg three times a day (150 to 300 mg/day) in patients with creatinine clearance of at least 60 mL/min. The value of this Savings Offer is limited to $175 per use or the amount of your co-pay, whichever is less - This Savings Offer is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plans or other health or pharmacy benefit programs - You must deduct the savings received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf - You are responsible for reporting use of this Savings Offer to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using this Savings Offer, as may be required. I take 150mg Lyrica 2xdaily. Headache (1.9-3.9%) 3. Base the dose adjustment in patients with renal impairment on creatinine clearance (CLcr), as indicated in Table 2. {* traditionalSignIn_signInButton *} LYRICA CR Dosage Adjustment Based on Renal FunctionWe comply with the HONcode standard for trustworthy health information - Consider more frequent assessment for patients who are already routinely monitored for ocular conditions. In addition to the daily dose adjustment, administer a supplemental dose immediately following every 4-hour hemodialysis treatment (see Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Then refer to Table 2 to determine the corresponding renal adjusted dose. Recommended Dosage for Adults and Pediatric Patients 1 Month and OlderTable 2. The dose may be increased to 300 mg/day within 1 week based on efficacy and tolerability.Although LYRICA was also studied at 600 mg/day, there is no evidence that this dose confers additional significant benefit and this dose was less well tolerated. The recommended starting dose is 75 mg two times a day (150 mg/day). There were reports of life-threatening angioedema with respiratory compromise requiring emergency treatment. (For example: A patient initiating LYRICA CR therapy for postherpetic neuralgia with normal renal function [CLcr greater than or equal to 60 mL/min], receives a single daily dose of 165 mg/day pregabalin.

The value of this Savings Offer is limited to $175 per use or the amount of your co-pay, whichever is less - This Savings Offer is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plans or other health or pharmacy benefit programs - You must deduct the savings received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf - You are responsible for reporting use of this Savings Offer to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using this Savings Offer, as may be required. 2 posts • Page 1 of 1. To use this dosing table, a… {* preferredLanguage *}

{* #userInformationForm *} When discontinuing LYRICA, taper gradually over a minimum of 1 week Because LYRICA is eliminated primarily by renal excretion, adjust the dose in adult patients with reduced renal function The maximum recommended dose of LYRICA is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Inform patients taking LYRICA that dizziness and somnolence may impair their ability to perform potentially hazardous tasks, such as driving or operating complex machinery, until they have sufficient experience with LYRICA to determine its effect on cognitive and motor function. There is evidence from case reports, human studies, and animal studies associating LYRICA with serious, life-threatening, or fatal respiratory depression when co-administered with central nervous system (CNS) depressants, including opioids, or in the setting of underlying respiratory impairment.

Discontinue LYRICA immediately in patients with these symptoms. Patients who are taking other drugs associated with angioedema, such as angiotensin-converting enzyme inhibitors (ACE inhibitors), may be at increased risk of developing angioedema. Joint swelling (1.9%) 13. Administer a supplemental dose of LYRICA immediately following every 4-hour hemodialysis treatment. Conversion from LYRICA Capsules or Oral Solution to LYRICA CRTable 2. Specific symptoms included swelling of the face, mouth (tongue, lips, and gums), and neck (throat and larynx). By using this Savings Offer, eligible patients may receive a savings of up to $175 per fill off their co-pay or out-of-pocket costs. Note: the information below includes the Part I: Health Professional Information. Doses can be …

(For example: A patient initiating LYRICA therapy for postherpetic neuralgia with normal renal function (CLcr greater than or equal to 60 mL/min), receives a total daily dose of 150 mg/day pregabalin.

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