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With the highest maternal dosage, the expected infant dose is about 1% of a typical infant dose.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Acyclovir is approved by the Food and Drug Administration as a prescription drug that is commonly used as a topical, injectable, and oral treatment for genital herpes and cold sores. However, given the small size of the registry, the data is not sufficient to evaluate the risk for less common defects or to permit reliable or definitive conclusions regarding the safety of this drug during pregnancy. for valtrex it's the 500mg twice a day dose for the last month of pregnancy.
Initial treatment: 200 mg PO q4hr while awake (5 times daily) for 10 days or 400 mg PO q8hr for 7-10 days. Precautions to Take While Taking Acyclovir During PregnancyPrecautions to Take While Taking Acyclovir During Pregnancy Does it have any side effects? Herpes refers to a group of viruses that cause a variety of herpes infections including genital herpes, shingles, chicken pox (also chickenpox), cold sores, and encephalitis (inflammation of the brain). To see the full article, log in or purchase access.Medical Management of Pregnant Women with Primary HSV InfectionMedical Management of Pregnant Women with Recurrent HSV InfectionReprinted with permission from Baker DA.
Indication Valacyclovir Acyclovir Famciclovir; First clinical episode. Genital Herpes .
Consumption of Acyclovir in pregnancy has not lead to any kind of pregnancy complications as well till date, studies show.
Teratogenicity was not seen when administered to animal models throughout the period of major organogenesis. From 1984 to 1999, a Pregnancy Registry established by the manufacturer and the Centers for Disease Control and Prevention (CDC) collected data for 749 pregnancies (756 outcomes) and found the rate of birth defects for women exposed to systemic drug during the first trimester of pregnancy approximated that of the general population.
The information on this website is of a general nature and available for educational purposes only and should not be construed as a substitute for advice from a medical professional or health care provider.
AU TGA pregnancy category: B3 US FDA pregnancy category: B Comments: -This drug has been safely used to treat genital herpes in women in all stages of pregnancy.-Women who acquire genital herpes simplex virus (HSV) during late pregnancy should be managed in consultation with maternal-fetal medicine and infectious-disease specialists. acyclovir is 400mg 3x/day for the last month of pregnancy. The dosage of acyclovir during pregnancy mainly depends on the severity of your condition. It may even help in reducing the length and severity of the outbreaks. All rights Reserved. We extend this analysis by adding quality-adjusted life year measurements and considering women with a diagnosed history of herpes simplex virus infection but without recurrence in pregnancy. The Committee on Practice Bulletins of the American College of Obstetricians and Gynecologists (ACOG) has developed a practice bulletin on the management of herpes in pregnancy. Is Acyclovir Safe During Pregnancy? Nongenital lesions should be covered with an occlusive dressing before vaginal delivery.The ACOG guidelines also discuss the following: how the diagnosis of HSV infection can be confirmed; when vaginal delivery is appropriate in patients with active HSV infection and ruptured membranes; how to manage women with active HSV infection and preterm rupture of membranes; which invasive procedures are contraindicated in women with HSV infection; and whether women with active HSV infection should breastfeed.
You may be prescribed 200 mg that should be taken 4 to 5 times a day or 400 mg taken 3 times a day, depending on your condition. There are no controlled data in human pregnancy. One of the largest studies taking into consideration more than 1500 children revealed no side effects when looked at the aspect of birth defects.
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