metronidazole mechanism of action usmle micardis

Vaginal fluid pH is > 4.5. Metronidazole, a nitroimidazole, exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Copyright © 2020 Lineage Medical, Inc. All rights reserved. These metabolites form linkages with important enzymes and deactivate them. E

Objective: To investigate the possible disulfiram-like properties of metronidazole and ethanol in human volunteers. Category Drug Comment Antiasthmatics aminophylline theophylline Especially but not exclusively above therapeutic levels Antibiotics isoniazid lindane metronidazole nalidixic acid penicillins Vitamin B6 supplement may protect Especially with renal failure Antidepressants tricyclics serotonin-specific agents bupropion Rarely a practical problem; desipramine may be preferable … (Bacterial vaginosis) Introduction: Mechanism of action

In addition, metronidazole metabolites are taken up into bacterial DNA and form unstable molecules that damage the DNA.In the organisms, metronidazole is taken up by diffusion and non enzymatically reduced, forming free radical toxic metabolites. Acyclovir is selectively acted upon by the viral thymidine kinase. Nucleic acid amplification testing for gonorrhea and chlamydia is negative. She is started on metronidazole. There are clue cells with a stippled appearance on the outer margins on microscopic testing of the vaginal fluid. USMLE First Aid 2011 Learn with flashcards, games, and more — for free. Type in at least one full word to see suggestions list Question Importance

Type in at least one full word to see suggestions list Genetic Implication. All volunteers received ethanol 0.4 g/kg at the beginning of the study. Acyclovir is an antiviral drug used mainly for herpes zoster infection. mechanism of action Activity against most obligate anaerobes occurs through a four-step process: Entry into the microorganism – Metronidazole is a low molecular weight compound that diffuses across the cell membranes of anaerobic and aerobic microorganisms. Entamoeba histolytica is a protozoan that causes the disease amebiasis. QID: It is an option for a first episode of mild-to-moderate Clostridium difficile colitis if vancomycin or fidaxomicin is unavailable. In addition, metronidazole metabolites are taken up into bacterial DNA and form unstable molecules that damage the DNA.Giardia lamblia is a protozoan parasite that infects the small intestine causing giardiasis.

Metronidazole is the current first-line therapy for Giardia infections.Metronidazole is used in the treatment of Entamoeba.

Metronidazole, marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. Rarely numbness, lung problems, or liver problems may occur. L 1 Leuprolide is an injectable, man-made hormone that is used for treating prostate cancer, endometriosis, central precocious puberty (early onset of puberty), and fibroids. Blocks protein synthesis by binding to the 50S ribosomal subunit inhibiting protein translocationBinds to the 30S ribosomal subunit preventing attachment of the aminoacyl-tRNA Bacterial vaginosis is characterized by an overgrowth of bacteria within the vaginal canal which results in greyish discharge and fishy odor. Sorry, this question is for Mechanism of Action. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis.

Quickly memorize the terms, phrases and much more. QID: Mechanism of Action Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II).

Metronidazole is commonly used in the treatment of anaerobic infections below the diaphragm while clindamycin is used for anaerobic infections above the diaphragm.

It is taken by mouth. Common side effects include a metallic taste in the mouth and a disulfiram-like reaction with alcohol.

Common side effects include nausea, loss of appetite, diarrhea, and headaches.

There are clue cells with a stippled appearance on the outer margins on microscopic testing of the vaginal fluid.

Remember more in less time and boost your test scores with Picmonic, the world’s best visual mnemonic learning resource and study aid for medical school, nursing school, and more!We use cookies to offer you a better experience and to analyze site traffic. It is similar to but stronger than human gonadotropin releasing hormone (GnRH). (M1.MC.13.63) Metronidazole is available by mouth, as a cream, a L1\L2 Evidence These metabolites form linkages with important enzymes and deactivate them. Start learning today for free!

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