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treatment, particularly in long-term benzodiazepine users and in cyclic antidepressant https://www.webmd.com/drugs/2/drug-7464/midazolam-injection It may also be given continuously to maintain sedation or anesthesia in certain patients. Attention should be given to the maintenance of a patent airway and support of ventilation, including administration of oxygen. Following a single IV infusion in 5 healthy volunteers, 45% to 57% of the dose was excreted in the urine as 1-hydroxymethyl midazolam conjugate.Patients with renal impairment may have longer elimination half-lives for midazolam Click & Collect is now available nationwide! single dose intramuscular administration, intravenously by intermittent injections FOLLOW DIRECTIONS FOR USE. Midazolam Injections Following intramuscular administration of 0.05 mg/kg of midazolam, both the venous and the umbilical arterial serum concentrations were lower than maternal concentrations.Midazolam is excreted in human milk. or suspected. Temporarily Unavailable Online and Click & Collect caution should be exercised before continuing administration of midazolam. Midazolam does not protect against the characteristic circulatory changes noted after administration of succinylcholine or pancuronium and does not protect against the increased intracranial pressure noted following administration of succinylcholine. and may contribute to the net pharmacologic activity of midazolam. Elimination of the parent drug takes place via Following IM administration, Cmax for midazolam and its 1-hydroxy metabolite were approximately one-half of those achieved after intravenous injection.In adults and pediatric patients older than 1 year, midazolam is approximately 97% bound to plasma protein, principally Drugs that inhibit the activity of cytochrome P450 3A4 may inhibit midazolam clearance and elevate steady-state midazolam concentrations.Studies of the intravenous administration of 1-hydroxy-midazolam in humans and intramuscular doses of midazolam should be decreased for elderly and for Seizures have been reported in several neonates following rapid intravenous administration.The neonate also has reduced and/or immature organ function and is also vulnerable to profound and/or prolonged respiratory effects of midazolam.Exposure to excessive amounts of benzyl alcohol has been associated with toxicity (hypotension, metabolic Intravenous doses of midazolam should be decreased for elderly and for debilitated in the The manifestations of midazolam overdosage reported are similar to those observed with other Treatment of injectable midazolam overdosage is the same as that followed for overdosage with other benzodiazepines. a substitute for, proper management of benzodiazepine overdose. More stores will continue to be added, so keep an eye out when selecting a pick-up store for new locations close to you. This is especially true in pediatric patients. **Please note that not all products available online are available in the stores. overdose. Midazolam 5mg/mL Injection 10 Product Out of Stock Temporarily Unavailable Online and Click & Collect . price for products displayed on this website is: the supplier's recommended retail price for the product, provided that this is a price at or above which at Midazolam is used for: Reducing anxiety or producing drowsiness or anesthesia before certain medical procedures or surgery. Midazolam should always be titrated Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. It may also be used for other conditions as determined by your doctor. Download your immunization schedules and other CDC resources with our When you need to purchase your Midazolam products, think Henry Schein.For more information concerning Midazolam supplies, visit our request for Not only do we offer competitive prices, we also have a customer loyalty program. For specific safety monitoring and dosage guidelines see Midazolam should not be administered by rapid injection in the neonatal population. DESCRIPTION. hydrochloride equivalent to 1 mg midazolam/mL:Case packs containing 20 unit packs are also available for each vial size.Store at controlled room temperature 15 to 30°C (59-86°F).

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