preferred medication allegra

Besides dosing, there are some slight differences in how quickly or well the drugs work.

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles.
Fexofenadine hydrochloride is a racemate and exists as a zwitterion in aqueous media at physiological pH.Allegra is formulated as a tablet for oral administration. Note that every person is different. Select one or more newsletters to continue. Allegra is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 2 years of age and older. Provider Help Desk: (p) 888-420-9711 (f) 800-408-1088 | Member Help Desk: (p) 866-796-2463 (f) 207-287-8601 Prior Authorization (PA) Helpdesk (for … Because many drugs are excreted in human milk, caution should be exercised when fexofenadine hydrochloride is administered to a nursing woman.The recommended doses of fexofenadine hydrochloride in pediatric patients 6 months to 11 years of age are based on cross-study comparison of the pharmacokinetics of fexofenadine in adults and pediatric subjects and on the safety profile of fexofenadine hydrochloride in both adult and pediatric subjects at doses equal to or higher than the recommended doses.The safety and effectiveness of fexofenadine hydrochloride in pediatric patients under 6 months of age have not been established.The safety of fexofenadine hydrochloride is based on the administration of Allegra tablets at a dose of 30 mg twice daily demonstrated in 438 pediatric subjects 6 years to 11 years of age in 2 placebo-controlled 2-week seasonal allergic rhinitis trials. This means that despite what studies say, there are many people who do not experience any fatigue on Zyrtec or Xyzal.

Never use more than the recommended dose.Ask a doctor or pharmacist if it is safe for you to take Allegra if you are allergic to any drugs, or if you have kidney disease.FDA pregnancy category C. It is not known whether Allegra will harm an unborn baby.

The effectiveness of fexofenadine hydrochloride for the treatment of chronic idiopathic urticaria in patients 6 months to 11 years of age is based on the pharmacokinetic comparisons in adults and children and an extrapolation of the demonstrated efficacy of Allegra in adults with this condition and the likelihood that the disease course, pathophysiology and the drug's effect are substantially similar in children to that of adult patients. No evidence of carcinogenicity was observed in an 18-month study in mice and in a 24-month study in rats at oral doses up to 150 mg/kg of terfenadine (which led to fexofenadine exposures that were approximately 3 and 5 times the exposure at the maximum recommended daily oral dose of fexofenadine hydrochloride in adults [180 mg] and children [60 mg] respectively).In rat fertility studies, dose-related reductions in implants and increases in postimplantation losses were observed at an oral dose of 150 mg/kg of terfenadine (which led to fexofenadine exposures that were approximately 3 times the exposure at the maximum recommended human daily oral dose of 180 mg of fexofenadine hydrochloride based on comparison of AUCs). Do not take extra medicine to make up the missed dose.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include dry mouth, dizziness, or drowsiness.Avoid using antacids within 15 minutes before or after taking a medication that contains Allegra.

The individual apparent oral clearance estimates of fexofenadine were on average 44% and 36% lower in pediatric subjects 6 to 12 years (n=14) and 2 to 5 years of age (n=21), respectively, compared to adult subjects.Administration of a 15 mg dose of fexofenadine hydrochloride to pediatric subjects 6 months to less than 2 years of age and a 30 mg dose to pediatric subjects 2 to 11 years of age produced exposures comparable to those seen with a dose of 60 mg administered to adults.Across several trials, no clinically significant gender-related differences were observed in the pharmacokinetics of fexofenadine hydrochloride.The carcinogenic potential of fexofenadine was assessed using terfenadine studies with adequate fexofenadine exposure (based on plasma area-under-the-concentration vs. time [AUC] values).

Fexofenadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes /nose, sneezing, hives, and itching.


Open the package and peel back the foil from the tablet blister. Important information Do not use Allegra-D if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

You can opt-out at any time. Allegra and Zyrtec are both over-the-counter allergy medications. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function Based on increases in bioavailability and half-life, a dose of 60 mg once daily is recommended as the starting dose in adult patients with decreased renal function (mild, moderate or severe renal impairment).

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