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Quetiapine Sandoz SR Quetiapine Sandoz SR 200 mg are yellow coloured, round shaped, biconvex film coated tablets, debossed with ‘I2’ on one side and plain on otherQuetiapine Sandoz SR 300 mg are light yellow coloured, round shaped, biconvex film coated tablets, debossed with ‘Q300’ on one side and plain on other.Quetiapine Sandoz SR 400 mg are White coloured, round shaped, biconvex, film coated tablets debossed with ‘I4’ on one side and plain on other.Pack sizes of 6, 10, 20, 28, 30, 50, 60, 90, 100 and 120 tablets per pack are registered for all strengths. sodium valproate) (see section 4.4).The pharmacokinetics of quetiapine were not significantly altered by co-administration of the antidepressants imipramine (a known CYP 2D6 inhibitor) or fluoxetine (a known CYP 3A4 and CYP 2D6 inhibitor). Patients treated with any antipsychotic agent including quetiapine, should be observed for signs and symptoms of hyperglycaemia, (such as polydipsia, polyuria, polyphagia and weakness) and patients with diabetes mellitus or with risk factors for diabetes mellitus should be monitored regularly for worsening of glucose control. This page explains how interactions can cause your body to metabolize the drugs differently than intended. The 50 mg is not Your doctor will write the number of refills authorized on your prescription.Quetiapine can make your body less able to manage your temperature. Shifts in WBCs are defined as ≤ 3 x 10(29) Based on adverse event reports of metabolic syndrome from all clinical trials with quetiapine. Caution may be needed when prescribing quetiapine to patients with a history of alcohol or drug abuse.Given the primary central nervous system effects of quetiapine, quetiapine should be used with caution in combination with other centrally acting medicinal products and alcohol. (3) Note: The frequency is consistent to that observed in adults, but might be associated with different clinical implications in children and adolescents as compared to adults.Reporting suspected adverse reactions after authorisation of the medicinal product is important. The rates of weight gain ≥7% of baseline body weight in the active arm vs. placebo were 17% vs. 2.5% in the schizophrenia and bipolar mania trials, and 113.7% vs. 6.8% in the bipolar depression trial. Day 4: 300 mg daily, taken at bedtime. In short-term, placebo-controlled monotherapy clinical trials in major depressive disorder the aggregated incidence of extrapyramidal symptoms was 5.4% for quetiapine prolonged release and 3.2% for placebo. 2 QUALITATIVE QUANTITATIVE COMPOSITION: For 300 mg: Each prolonged release tablet contains 300 mg Quetiapine (as Quetiapine Fumarate) Excipient(s) with known effect: 61.05 mg Lactose monohydrate and 5.3 mg sodium per tablet . A population-based retrospective study of quetiapine for the treatment of patients with MDD, showed an increased risk of death during use of quetiapine in patients aged >65 years. Effects related to elevated prolactin levels were seen in rats, although these are not directly relevant to humans (see section 5.3).Given its primary central nervous system effects, quetiapine may interfere with activities requiring mental alertness. This is not recommended as standard treatment, because of potential negative effect of physostigmine on cardiac conductance. However, it’s thought that it helps regulate the amount of certain chemicals (dopamine and Quetiapine oral tablet may cause drowsiness. )Concomitant use of quetiapine with a strong hepatic enzyme inducer such as carbamazepine or phenytoin substantially decreases quetiapine plasma concentrations, which could affect the efficacy of quetiapine therapy. The dosage will then need to be increased according to the dosage schedule from when you first started the medication.Quetiapine oral tablet is used for long-term treatment. In addition, physicians should consider the potential risk of suicide-related events after abrupt cessation of quetiapine treatment, due to the known risk factors for the disease being treated.Other psychiatric conditions for which quetiapine is prescribed can also be associated with an increased risk of suicide related events. 18 mm length and 8.8 mm width) film-coated tablets with score line on both sides.- for the treatment of moderate to severe manic episodes in bipolar disorder - for the treatment of major depressive episodes in bipolar disorder- for the prevention of recurrence of manic or depressed episodes in patients with bipolar disorder who previously responded to quetiapine treatment.Different dosing schedules exist for each indication.

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