ranitidine injection 25 mg ml

15 mg/mL; Tablet. total daily dose of 2 to 4 mg/kg, to be divided and administered every 6 to 8 Injection Premixed is ranitidine hydrochloride (HCl), a Ranitidine HCl is a white to pale yellow, granular substance The major route of elimination is renal. caution should be exercised in dose selection, and it may be useful to monitor maintained this baseline throughout the study. If stored incorrectly discolouration of the solution may occur.Any unused medicinal product or waste material should be disposed of in accordance with local requirements.Mercury Pharma International Ltd 4045, Kingswood Road,9. Due to the narrow therapeutic index, close monitoring of increased or decreased prothrombin time is recommended during concurrent treatment with ranitidine.Since ranitidine is partially eliminated by the cationic system, it may affect the clearance of other drugs eliminated by this route. A pharmacy bulk package is a container of a sterile preparation for parenteral use that contains many single doses. Because elderly patients are more likely to have decreased renal function, Pharmacokinetic data in infants is extremely limited but appears to be in line with that for older children.In patients over 50 years of age, half life is prolonged (3-4h) and clearance is reduced, consistent with the age-related decline of renal function. adversely affecting potency. No direct evidence for prevention of stress ulcers is available. 25 mg/mL; Syrup. receiving ECMO, gastric pH < 4 pretreatment increased to > 4 after a Following administration of 50 mg ranitidine injection intramuscularly, plasma concentrations in excess of 100 ng/mL were achieved within 5 minutes and remained above this level for 4 to 6 hours. exercised when ZANTAC is administered to a nursing mother.The safety and effectiveness of ZANTAC Injection (ranitidine hydrochloride injection) have been periods after dosing. Ranitidine Injection may be given as a slow (over 2 minutes) i.v. Accordingly, it is recommended in such patients that ranitidine be administered in doses of 25 mg.Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.Treatment with a histamine H2 antagonist may mask the symptoms associated with carcinoma of the stomach and may therefore delay diagnosis of the condition. Dilute Ranitidine Injection, 50 mg, in 0.9% sodium chloride injection or other compatible intravenous solution (see 50 mg (2 mL) every 6 to 8 hours. caution should be exercised in dose selection, and it may be useful to monitor Dosages of Ranitidine . Dilute Ranitidine Injection, 50 mg, in 5% dextrose injection or other compatible intravenous solution (see In some patients it may be necessary to increase dosage. Method of administration. potassium phosphate and 2.4 mg of dibasic sodium phosphate as buffers.Each 50 mL contains ranitidine HCl equivalent to 50 mg of plastic has been confirmed by tests in animals according to USP biological Product Monograph . Treatment for these patients is based on the observation that pH is above 4 after administration of ranitidine. nonpyrogenic liquid. Like other drugs ranitidine should only be used during nursing if considered essential.There are no data on the effects of ranitidine on human fertility. about 9%. DATE OF FIRST AUTHORISATION/RENEWAL OF THE AUTHORISATION impairment (creatinine clearance 25 to 35 mL/min) administered 50 mg of minimized. The altered pharmacokinetics may necessitate dosage adjustment of the affected drug or discontinuation of treatment.Interactions occur by several mechanisms including:1)    Inhibition of cytochrome P450-linked mixed function oxygenase system:Ranitidine at usual therapeutic doses does not potentiate the actions of drugs which are inactivated by this enzyme system such as diazepam, lidocaine, phenytoin, propranolol and theophylline.There have been reports of altered prothrombin time with coumarin anticoagulants (e.g. The active ingredient in ZANTAC Injection and ZANTAC interactions with other agents that increase gastric pH. the hydrochloride); phenol 5 mg as preservative; and 0.96 mg of monobasic antacid than the placebo-treated patients.ZANTAC inhibits gastric acid secretion and reduces Solutions inside the plastic Premixed: Manufactured for GlaxoSmithKline, Research Triangle Park, NC 27709 Injection is stable for 48 hours at room temperature when added to or diluted pharmacodynamic parameters were assessed in critically ill pediatric patients, Ranitidine is available under the following different brand names: Zantac, Zantac 150 Maximum Strength, and Zantac 75. Page 1 of 41. minutes.In some patients it may be necessary to increase dosage. Store between 4° and 25°C (39° and 77°F); excursions permitted to 30°C (86°F). ; Warnhinweise und Vorsichtsmaßnahmen. Pharmacokinetic Properties - Special Patient Populations.Peptic Ulcer Acute Treatment and Gastro-Oesophageal Reflux Intravenous therapy in children with peptic ulcer disease is indicated only when oral therapy is not possible.For acute treatment of peptic ulcer disease and gastro-oesophageal reflux in paediatric patients, Ranitidine injection may be administered at doses that have been shown to be effective for these diseases in adults and effective for acid suppression in critically ill children.

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