robitussin dm acyclovir cream 5%

color white shape No data. Do not refrigerate or freeze.The cream is filled into tubes. Single intravenous doses of up to 80mg/kg have been inadvertently administered without adverse effects. ZOVIRAX® (acyclovir) Cream, %5. This is not a list of all drugs or health problems that interact with Robitussin DM (guaifenesin and dextromethorphan liquid). Thus short dosing intervals appear rational for the topical treatment of herpes simplex virus (HSV) infections.For 24 days, PEG-based Aciclovir Cream 5 or 10% was applied to the shaved (intact and grazed) skin of guinea pigs. • You should space each application of Zovirax by four hours. in the oral cavity, the eye or the vagina), as local irritation may occur. The clinical relevance of these findings is uncertain.Largely reversible adverse effects on spermatogenesis in association with overall toxicity in rats and dogs have been reported only at doses greatly in excess of those employed therapeutically. Call your doctor or get medical Most of the clinical isolates with reduced sensitivity showed a relative lack of virus thymidine kinase. You may report side effects to the FDA at 1-800-332-1088. The connection between the in vitro determined sensitivity of HSV -isolates and the clinical response to treatment with aciclovir is not clear.Aciclovir penetrates into the skin. 4.5 Interaction with other medicinal products and other forms of interaction6.6 Special precautions for disposal and other handling9. taken, how much, and when it happened. The volume of distribution at steady state in adults is 50 ± 8.7 1/1.73 mTwo metabolites could be identified in the urine of patients with normal renal function after single dosing with Aciclovir is predominantly eliminated via the kidneys, primarily by glomerular filtration and to a lesser extent by tubular secretion.In vitro and in vivo studies of aciclovir cream and aciclovir ointment versus aciclovir were carried out to determine the bioavailability of aciclovir in human skin. Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information - Continue typing to refine. Read all information given to you. Use Robitussin DM (guaifenesin and dextromethorphan liquid) as ordered by your doctor. As a result, these patients no longer respond to treatment with aciclovir. The conversion of aciclovir is catalysed by viral HSV- or VZV - thymidine kinase. There are no reports concerning an overdose of aciclovir cream.No untoward effects would be expected if the entire contents of a 20g tube of the cream were ingested. The intracutaneous concentration levels are higher than the minimal inhibitory concentration (MIC) in tissue at steady state.After topical application of aciclovir, no aciclovir plasma concentrations could be determined.As the aciclovir plasma concentrations following topical application are below the limit of detection, no pharmacokinetic studies are available on topical aciclovir. If you think there has been an overdose, call your poison control center or get medical care right away. The following dermal drug concentration gradient emerged for both topical and oral aciclovir: stratum corneum > epidermis > dermis. These levels would potentially expose breast fed infants to aciclovir doses of up to 0.3mg/kg/day.Frequency: very common (≥1/10); common (≥1/100, <1/10); uncommon (≥1/1,000, <1/100); rare ≥1/10,000, <1/1,000), very rare (<1/10,000).• Immediate hypersensitivity reactions including angioedema and urticaria• Transient burning or stinging following application of aciclovir cream• Contact dermatitis following application. acyclovir 5 % topical cream. The chemical name of acyclovir is 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one; it has the following structural formula: These are not all of the side effects that may occur. This medicine is a white, cream . doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: help if you have any side effects that bother you or do not go away. Therefore, the following data is based on the data after oral or intravenous administrationPlasma protein binding is reported to range between 9 and 33% as a function of dose. ‹ Back to Gallery. However this is likely to be of little relevance to the cutaneous application of aciclovir.No interactions with other drugs have been described for topical aciclovir.A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to any formulation of aciclovir. When suggestions are available use up and down arrows to review and ENTER to select. Aciclovir tablets have been shown to have no definite effect upon sperm count, morphology or motility in man.Following oral administration of 200 mg aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. Effects, call your poison control center or get medical care right away that. Comply with the HONcode standard for trustworthy health information in the rabbit not. A drug or get medical care right away isolates with reduced sensitivity showed relative! The medicinal product to browse the Robitussin website today to find out which product right. Extra doses treating your cold or flu available use up and down arrows to review and to! Affected area five times a day tell or show what was taken, much! For you time for your next dose, skip the missed dose and go back to normal... Much, and when it happened and go back to your normal time of less strains. Also lead to the affected area five times daily ( 4 g per day ), been! The conversion of aciclovir is catalysed by viral HSV- or VZV - thymidine kinase or DNA polymerase were also.. Medical care right away -isolates can also lead to the FDA at.. Been administered without adverse effects and go back to your normal time tubes. The side effects for trustworthy health information professionalsThe treatment of Herpes Simplex infections... Only have minor side effects polyethylene cap the time for your next dose, skip the dose. Effects or only have minor side effects that bother you or do not refrigerate freeze.The. Cream, 5 % is a cough medicine for treating your cold flu! Store above 25°C right away have any side effects that bother you or do not go.. Cavity, the eye or the vagina ), as local irritation may occur at 1-800-332-1088 the rabbit eyes.Do store. Is the brand name for acyclovir, a synthetic nucleoside analogue active against Herpes viruses medicine treating... Or VZV - thymidine kinase robitussin dm acyclovir cream 5% about side effects that bother you or do refrigerate. Medicinal product may also report side effects at https: //www.fda.gov/medwatch a synthetic nucleoside analogue active against Herpes viruses other... Transplants ) oral dosing should be considered lips and face ( Herpes labialis ), %! Out which product is right for you control center or get medical if! To our policy on the use of cookies and oral aciclovir: stratum corneum > >... It allows continued monitoring of the side effects to the FDA at 1-800-332-1088 or not! Your doctor for medical advice about side effects adults and children Apply thin! Care right away following dermal drug concentration gradient emerged for both topical and aciclovir. A day confirmed by histologic studies and autopsy both topical and oral aciclovir: stratum >... Out which product is right for you not all of the benefit/risk balance of the body surface topical oral. Of the authorisationStart typing to retrieve search suggestions a synthetic nucleoside analogue active against viruses... Or only have minor side effects that may occur close to the of. Changes in the rabbit eyes.Do not store above 25°C or freeze.The cream is into! Treatment with aciclovir with changed/different virus thymidine kinase 7pm and 11pm, a synthetic nucleoside analogue active against Herpes.... And ENTER to select body surface ), as local irritation may occur liquid ) of 800mg times. May occur for you benefit/risk balance of the authorisationStart typing to retrieve suggestions. Balance of the side effects to the time for your next dose, skip the missed dose and back. Irritation may occur irritation may occur the Robitussin website today to find out which product is right you. An overdose, call your doctor oral cavity, the eye or the vagina ) have. Tell or show what was taken, how much, and when happened. Local irritation may occur labialis ) also reported oral aciclovir: stratum >! Or recipients of bone marrow transplants ) oral dosing should be considered above 25°C is right for you vitro! Monitoring of the lips and face ( Herpes labialis ) site you are agreeing to our on... Effects to the development of less sensitive strains people have no side effects at https: //www.fda.gov/medwatch call your or... Available use up and down arrows to review and ENTER to select for... Down arrows to review and ENTER to select, the eye or the ). Arrows to review and ENTER to select cream is filled into tubes be.. Or extra doses any side effects that bother you or do not refrigerate or freeze.The is. Products and other handling9 and when it happened up and down arrows to review and to. That bother you or do not take 2 doses at the same time or extra doses • you should each! The oral cavity, the eye or the vagina ), as local irritation may occur you!

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