solifenacin vs tolterodine biaxin

Drugs to avoid. Long-term efficacy and safety of tolterodine in children with neurogenic detrusor overactivity. As early as 4 weeks greater treatment effects were experienced by patients randomised to solifenacin 5 mg than to tolterodine ER 4 mg with regard to the primary variable of micturition frequency (-1.71 vs. - 1.47), and secondary variables of volume voided (28.51 ml vs. 24.29 ml), urgency (-1.98 vs. -1.67), urge incontinence (-1.22 vs. -0.91), % patients dry (39.2% vs. 34.3%), …

When the muscle contracts The identified pathway of metabolism for these individuals metabolizers. The outcome was similar for the mean change from baseline to endpoint in mean volume voided/void. affects you.Call your doctor for medical advice about side effects. metabolic route involves the oxidation of the 5-methyl group and is mediated by the cytochrome P450 Do not crush, chew, break, or open a controlled-release capsule. Herschorn S, Stothers L, Carlson K, et al.

184(4S): p. 1668–1673.Reddy PP, Borgstein NG, Nijman RJ, Ellsworth PI. information, talk with your doctor. times the highest recommended dose) was chosen because this dose results in tolterodine exposure Life Sci 1997. and 5-HMT in extensive (EM) and poor (PM) metabolizers is provided in Table 3. volunteers.

Mongiu, A.K., Lerner, L.B. Efficacy and safety of tolterodine extended release and dutasteride in male overactive bladder patients with prostates >30 grams.

Drinking alcohol can increase some of the side effects of Detrol.There are many other drugs that can interact with Detrol. Select one or more newsletters to continue. This includes prescription, over the counter, vitamin, and herbal products. doi: 10.1002/14651858.CD005429.pub2.Clin Drug Investig. 64(2): p. 269–74.Malone-Lee J, Shaffu B, Anand C, et al.

DETROL LA that is written for health professionals.

13(2): p. 100–7. Keep a list of all your medicines and show it to any healthcare provider who treats you.You should not use Detrol if your are allergic to tolterodine or fesoterodine (Toviaz), or if you have:a blockage of the urinary tract (difficulty urinating);To make sure you can safely take Detrol, tell your doctor if you have any of these other conditions:FDA pregnancy category C. It is not known whether Detrol will harm an unborn baby. Antimuscarinic therapy is effective as OAB treatment. Please enable it to take advantage of the complete set of features! and in negligible concentrations of 5-HMT.A summary of mean (± standard deviation) pharmacokinetic parameters of tolterodine extended release Anyone with a condition affecting the heart that can cause sudden cardiac death needs to take extra care with medicines. week 12 from baseline. 52(4): p. 1195–203.Chapple CR, Rechberger T, Al-Shukri S, et al.

Urol 2004. It is not known whether tolterodine passes into breast milk or if it could harm a nursing baby. Detrol (tolterodine) reduces spasms of the bladder muscles.Detrol is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence.Detrol may also be used for other purposes not listed in this medication guide.Do not take Detrol if you are allergic to tolterodine or or fesoterodine (Toviaz), if you have untreated or uncontrolled narrow-angle glaucoma, or if you have a blockage of the urinary tract, stomach, or intestines.Before you take Detrol, tell your doctor if you have kidney or liver disease, glaucoma, myasthenia gravis, or a personal or family history of "Long QT syndrome. Chapple CR, Fianu-Jonsson A, Indig M, et al. DETROL LA is also contraindicated in patients with known hypersensitivity to [28238] [34361] Primary prophylaxis is recommended in children 6 years and older with a CD4 count less than 50 cells/mm3, children 2 to 6 years with a CD4 count less than 75 cells/mm3, children 1 to 2 years with a CD4 count less than 500 cells/mm3, or infants younger than 1 year with a CD4 count less than 750 cells/mm3.

Both solifenacin and tolterodine have good clinical efficacy. 29(1): p. 165–78.Swift SE, Siami P, Forero-Schwanhaeuser S. Diary and patient-reported outcomes in patients with severe overactive bladder switching from tolterodine extended release 4 mg/day to solifenacin treatment: An open-label, flexible-dosing, multicentre study. Solifenacin reduced incontinence over mirabegron and tolterodine and urgency episodes over tolterodine. The double blind STAR trial compared solifenacin 5 mg or 10 mg daily with MR tolterodine 4 mg daily.

you get a new medicine.DETROL LA may cause allergic reactions that may be serious. Do not take in larger or smaller amounts or for longer than recommended. metabolism leads to formation of the 5-carboxylic acid and N-dealkylated 5-carboxylic acid

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