sumatriptan autoinjector lozol
Apprise patients of the importance of this follow-up [see Warnings and Precautions (Inform patients that use of sumatriptan injection within 24 hours of another triptan or an ergot-type medication (including dihydroergotamine or methysergide) is contraindicated [see Contraindications Advise patients to notify their healthcare provider if they become pregnant during treatment or plan to become pregnant [see Advise patients to notify their healthcare provider if they are breastfeeding or plan to breastfeed [see Use in Specific Populations Treatment with sumatriptan injection may cause somnolence and dizziness; instruct patients to evaluate their ability to perform complex tasks after administration of sumatriptan injection.Instruct patients to read the Instructions for Use before starting therapy. Following a 6 mg subcutaneous injection into the deltoid area of the arm, the systemic clearance of sumatriptan was 1,194 ± 149 mL/min and the terminal half-life was 115 ± 19 minutes. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Time to Relief of Cluster Headache from Time of InjectionStore at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature]. Look inside the cap, check that the gray needle cover is inside.You are now ready to inject the medicine, go to step 9Without pressing the blue button, push the pen firmly against your skin.As long as the blue circle is visible in the medicine window, Keep the pen pressed against your skin for the next steps10.
Discard the whole sumatriptan injection autoinjector after use.his Patient Information and Instructions for Use has been approved by the U.S. Food and Drug Administration. Proportion of Patients with Pain Relief and Relief of Migraine Symptoms after 1Table 4. The osmolality of the injection is between 275 and 315 mOsm/kg.Sumatriptan binds with high affinity to human cloned 5-HT Significant elevation in blood pressure, including hypertensive crisis, has been reported in patients with and without a history of hypertension [see Warnings and Precautions ( In healthy volunteers (N = 18), a trial evaluating the effects of sumatriptan on peripheral (small vessel) arterial reactivity failed to detect a clinically 359 significant increase in peripheral resistance. Advise the patient to read the FDA-approved patient labeling (Patient Information and Instructions for Use).Inform patients that sumatriptan injection may cause serious cardiovascular side effects such as myocardial infarction or stroke. Sumatriptan can cause serious side effects such as death, heart attack, stroke, increased high blood pressure, fast heartbeat, changes in mental status like hallucination, agitation and coma, tight muscles or … Do not attempt to re-engage the safety lock at any time.11. Sumatriptan Succinate Injection Kit, 6 mg, containing 1 autoinjector pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case (NDC 66993-084-98). These highlights do not include all the information needed to use To report SUSPECTED ADVERSE REACTIONS, contact Dr.Reddy's Laboratories Inc., at 1-888-375-3784 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch2.2 Administration Using the Sumatriptan Autoinjector2.3 Administration of Doses of Sumatriptan Injection Other than 6 mg5.1 Myocardial Ischemia, Myocardial Infarction, and Prinzmetal’s Angina 5.3 Chest, Throat, Neck and /or Jaw Pain/Tightness/Pressure 7.4 Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine2.2 Administration Using the Sumatriptan Autoinjector2.3 Administration of Doses of Sumatriptan Injection Other than 6 mg5.1 Myocardial Ischemia, Myocardial Infarction, and Prinzmetal’s Angina 5.3 Chest, Throat, Neck and /or Jaw Pain/Tightness/Pressure Adverse Reactions in Pooled Placebo-Controlled Trials in Patients with Migraine (Studies 2 and 3)7.4 Selective Serotonin Reuptake Inhibitors/Serotonin NorepinephrineDisease-Associated Maternal and/or Embryo/Fetal Risk:Table 2. Provide patients instruction on the proper use of sumatriptan injection if they are able to self-administer sumatriptan injection in medicaly unsupervised situations. The chemical name of Lozol is 1-(4-chloro-3-sulfamoylbenzamido)-2-methylindoline, and its molecular weight is 365.84. Use the device immediately once the cap has been removed; it is advised not to postpone the injectionKeep the Sumatriptan Autoinjector System out of the reach of children.7. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety.
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