sumatriptan nasal spray 20mg cipro

2002 Jan;249(1):94-9. doi: 10.1007/pl00007854.Diamond S, Elkind A, Jackson RT, Ryan R, DeBussey S, Asgharnejad M.Arch Fam Med. Medication overuse headache may present as migraine-like daily headaches or as a marked increase in frequency of migraine attacks. Keep your head level and remove the nozzle from your nostril. If there is evidence of CAD or coronary artery vasospasm, sumatriptan nasal spray, USP is contraindicated. The nasal spray should be administered into one nostril only. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens Inform patients that use of sumatriptan nasal spray, USP within 24 hours of another triptan or an ergot-type medication (including dihydroergotamine or methysergide) is contraindicated Caution patients about the risk of serotonin syndrome with the use of sumatriptan nasal spray, USP or other triptans, particularly during combined use with SSRIs, SNRIs, TCAs, and MAO inhibitors Inform patients that use of acute migraine drugs for 10 or more days per month may lead to an exacerbation of headache and encourage patients to record headache frequency and drug use (e.g., by keeping a headache diary) Advise patients to notify their healthcare provider if they become pregnant during treatment or plan to become pregnant Advise patients to notify their healthcare provider if they are breastfeeding or plan to breastfeed Treatment with sumatriptan nasal spray, USP may cause somnolence and dizziness; instruct patients to evaluate their ability to perform complex tasks after administration of sumatriptan nasal spray, USP.Inform patients that they may experience local irritation of their nose and throat. In offspring of pregnant rats treated orally with sumatriptan during organogenesis, there was a decrease in pup survival.

Percentage of Patients with Headache Response (No or Mild Pain) 2 Hours following TreatmentFigure 1. The effect was almost identical when the nasal spray was administered in the nostril on the non-painful side.

Apprise patients of the importance of this follow-up Inform patients that anaphylactic/anaphylactoid reactions have occurred in patients receiving sumatriptan nasal spray, USP. The estimated probability of patients taking a second dose or other medication for migraine over the 24 hours following the initial dose of study treatment is summarized in Figure 2.There is evidence that doses above 20 mg do not provide a greater effect than 20 mg. You can ask your healthcare provider or pharmacist for information about sumatriptan nasal spray, USP that is written for healthcare professionals.IMITREX and AMERGE are registered trademarks of the GSK group of companies. Do not change your dose without first talking with your healthcare provider.If you do not get any relief after your first nasal spray, do not use a second nasal spray without first talking with your healthcare provider.If your headache comes back after the first nasal spray or you only get some relief from your headache, you can use a second nasal spray 2 hours after the first nasal spray.Do not use more than 40 mg of sumatriptan nasal spray, USP in a 24-hour period.It is not known how using sumatriptan nasal spray, USP for a long time affects the nose and throat.If you use too much sumatriptan nasal spray, USP, call your healthcare provider or go to the nearest hospital emergency room right away.You should write down when you have headaches and when you use sumatriptan nasal spray, USP so you can talk with your healthcare provider about how sumatriptan nasal spray, USP is working for you.changes in color or sensation in your fingers and toes (Raynaud’s syndrome)stomach and intestinal problems (gastrointestinal and colonic ischemic events). Clinical data to determine the frequency of serious adverse reactions in pediatric patients who might receive subcutaneous, oral, or intranasal sumatriptan are not presently available.Clinical trials of sumatriptan nasal spray, USP did not include sufficient numbers of patients aged 65 and older to determine whether they respond differently from younger patients. In 4 of the 5 trials, there was a statistically significant greater percentage of patients with headache response at 2 hours in the 20-mg group when compared with the lower-dose groups (5 and 10 mg). As an overall judgement, only 2 of the 26 patients preferred nasal spray to injection. There were insufficient data to assess the impact of race on the incidence of adverse reactions.The following adverse reactions have been identified during postapproval use of sumatriptan tablets, sumatriptan nasal spray, and sumatriptan injection.

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