topical clindamycin while breastfeeding panadol

Clindamycin in human breast milk. 1975;112:806. [PMC free articleMatsuda S. Transfer of antibiotics into maternal milk. Only water-miscible cream, foam, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking. [1]Two women were treated with clindamycin 600 mg intravenously every 6 hours followed by 300 mg orally every 6 hours (time postpartum not stated). If oral or intravenous clindamycin is required by a nursing mother, it is not a reason to discontinue breastfeeding, but an alternate drug may be preferred. [Tissue and body fluid distribution of antibacterial agents in pregnant and lactating women]. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.Vaginal application is unlikely to cause infant side effects, although about 30% of a vaginal dose is absorbed. Clindets Pledget, Neuac, Onexton, Cleocin HCl, Cleocin Ovules, Clindacin PAC, Evoclin, Clindacin ETZ, Clindamax, Pledgaclin, ClindaReach Pledget, C/T/S, Clinda-Derm, Cleocin Phosphate, Clindets, Acanya, Z-Clinz 5, Z-Clinz 10, BenzaClin Carekit, Cleocin Pediatric, Cleocin Phosphate ADD-Vantage, Clindap-TWe comply with the HONcode standard for trustworthy health information -

Two women were treated with clindamycin 600 mg intravenously every 6 hours followed by 300 mg orally every 6 hours (time postpartum not stated). Infant side effects are unlikely with topical administration for acne; however, topical application to the breast may increase the risk of diarrhea if it is ingested by the infant. [PubMed Select one or more newsletters to continue. 1980;66:1030-1. 1984;5:57-60. Select one or more newsletters to continue. Zhonghua Fu Chan Ke Za Zhi. Clindamycin Levels and Effects while Breastfeeding Summary of Use during Lactation Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora. Available for Android and iOS devices.Noti A, Grob K, Biedermann M et al. [PubMedMatsuda S, Mori S, Azuma S. Clinical evaluation of clindamycin in gyneco-obstetrics. [3]Five women were given oral clindamycin 150 mg three times daily during the first 2 weeks postpartum. In an unspecified number of pregnant women given a 2% vaginal cream formulation for 7 days during their second trimester, 1.1% experienced abnormal labor compared with 0.5% of patients given placebo. [PMC free articleSteen B, Rane A. Clindamycin passage into human milk. 1982;13:661-4. Antibiotics Might Lower Effectiveness of Birth Control Pill Clindamycin has the potential to cause adverse effects on the breastfed infant's gastrointestinal flora. Breastmilk levels of clindamycin averaged 1.3 mg/L 4 hours after the dose. Letter. 1997;32:288-92. Chemotherapy (Tokyo). Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.

Regul Toxicol Pharmacol. [5]After a single dose of 600 mg of clindamycin intravenously to 15 women who were 1 month postpartum, milk clindamycin levels averaged 1.03 mg/L 2 hours after the dose. Can Med Assoc J. Peak milk levels after the intravenous dose were 2.65 mg/L at 3.5 hours after the dose in one and 3.1 mg/L at 30 minutes after the dose in the other. Clindamycin topical Breastfeeding Warnings This drug is excreted into breastmilk when given orally or intravenously. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. During the oral regimen, peak milk levels were 1.3 mg/L at 3.5 hours after the dose in the first woman and 1.8 mg/L at 2 hours after the dose in the other. 2003;38:317-25. Peak milk levels after the intravenous dose were 2.65 mg/L at 3.5 hours after the dose in one and 3.1 mg/L at 30 minutes after the dose in the other. Biol Res Pregnancy Perinatol. If you notice any symptoms in your child, contact their healthcare provider. Clindamycin might cause some gastrointestinal (GI) effects in a breastfeeding baby similar to those seen in adults (e.g. On day 6 of age, the infant resumed breastfeeding after discontinuation of maternal antibiotics with no further difficulties. The infant's stools were reported to have normal flora and the stools became guaiac negative 24 hours after discontinuation of breastfeeding. 1969;17:899-900.Smith JA, Morgan JR, Rachlis AR et al. Although the manufacturers generally recommend that this drug should be avoided while breastfeeding, the American Academy of Pediatrics classifies Clindomycin as compatible while breastfeeding. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. nausea, diarrhea, stomach pain, vomiting, diaper rash, thrush). Use is not recommended and a decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother. Maternal Levels.Two women were give clindamycin 150 mg orally.

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