what is unasyn used to treat reminyl

The dose of Unasyn in such patients should be administered less frequently in accordance with the usual practice for ampicillin (see Ampicillin has been found to be approximately 28% reversibly bound to human serum protein and sulbactam approximately 38% reversibly bound.The following average levels of ampicillin and sulbactam were measured in the tissues and fluids listed:Penetration of both ampicillin and sulbactam into cerebrospinal fluid in the presence of inflamed meninges has been demonstrated after IV administration of Unasyn.The pharmacokinetics of ampicillin and sulbactam in pediatric patients receiving Unasyn are similar to those observed in adults. Ampicillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. Mean half-life values were approximately 1 hour.Ampicillin is similar to benzyl penicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. However, it is not known whether the use of Unasyn in humans during labor or delivery has immediate or delayed adverse effects on the fetus, prolongs the duration of labor, or increases the likelihood that forceps delivery or other obstetrical intervention or resuscitation of the newborn will be necessary.Low concentrations of ampicillin and sulbactam are excreted in the milk; therefore, caution should be exercised when Unasyn is administered to a nursing woman.The safety and effectiveness of Unasyn have been established for pediatric patients one year of age and older for skin and skin structure infections as approved in adults. There are no data with Unasyn and allopurinol administered concurrently. These reactions are more apt to occur in individuals with a history of penicillin hypersensitivity and/or hypersensitivity reactions to multiple allergens. In patients treated with Unasyn the possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. Before therapy with a penicillin, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens. They do not treat viral infections (e.g., the common cold). Properly discard this product when it is expired or no longer needed. Unasyn and aminoglycosides should not be reconstituted together due to the Administration of Unasyn will result in high urine concentration of ampicillin. Use of Unasyn in pediatric patients is supported by evidence from adequate and well-controlled studies in adults with additional data from pediatric pharmacokinetic studies, a controlled clinical trial conducted in pediatric patients and post-marketing adverse events surveillance. The resultant solution will have a final concentration of approximately 100 mg/mL ampicillin and 50 mg/mL sulbactam. There have been reports of individuals with a history of penicillin hypersensitivity who have experienced severe reactions when treated with cephalosporins. (see In patients with impairment of renal function the elimination kinetics of ampicillin and sulbactam are similarly affected, hence the ratio of one to the other will remain constant whatever the renal function. If superinfections occur (usually involving Prescribing Unasyn in the absence of proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.Patients should be counseled that antibacterial drugs including Unasyn should only be used to treat bacterial infections. Hepatic toxicity is usually reversible; however, deaths have been reported. These reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena. Hepatic function should be monitored at regular intervals in patients with hepatic impairment.Unasyn may cause severe skin reactions, such as toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome (SJS), dermatitis exfoliative, erythema multiforme, and Acute generalized exanthematous pustulosis (AGEP). Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Peak ampicillin serum levels ranging from 109 to 150 mcg/mL are attained after administration of 2000 mg of ampicillin plus 1000 mg sulbactam and 40 to 71 mcg/mL after administration of 1000 mg ampicillin plus 500 mg sulbactam. ampicillin/sulbactam (unasyn ®) The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. In clinical trials, most children received a course of oral antimicrobials following initial treatment with intravenous Unasyn. The second, an oral form called sultamicillin, is …

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