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If you smoke, try to quit. Cut down on alcohol use. These include:Lifestyle factors can also affect your ability to have an erection. Read on to learn more about the relationships among ED, Zoloft, and mental health.SSRIs such as Zoloft work by increasing the amount of the neurotransmitter serotonin that is available in your brain. SSRI antidepressants. Michael Bihari, MD, is a board-certified pediatrician, health educator, and medical writer, and president emeritus of the Community Health Center of Cape Cod.Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. And if you have a substance abuse problem, seek help. If I had a patient with sexual dysfunction and a remote history of SSRI use, I have a hunch that if you bother working with the patient, you'll find there are other factors at play. Symptoms include genital numbness, decreased sex drive (libido), erectile dysfunction, failure to become aroused or orgasm, pleasureless or weak orgasm, and premature ejaculation. Sexual side effects are estimated to occur in over 50% of men on SSRI therapy. Cut down on alcohol use. Also, make time for some physical activity every day. The sensory changes may extend beyond the genital area to a … Subscribe and get access to all BMJ articles, and much more.You can download a PDF version for your personal record.If you are unable to import citations, please contact Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI). For some men, side effects decrease as the body adjusts to the medication. Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI). For others, the side effects don’t go away. For example, if you have high blood pressure and diabetes and take various medications that contribute to ED, all of those things could be causing ED. Antidepressants most likely to cause sexual side effects include: Selective serotonin reuptake inhibitors (SSRIs), which include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Pexeva) and sertraline (Zoloft). It helps with blood flow, weight control, and stress reduction.There are many possible causes for ED, and if you’re taking Zoloft, it may be the culprit. Examples of these conditions include:Certain medications can also cause ED. Our website services, content, and products are for informational purposes only. Our website services, content, and products are for informational purposes only. I'm not aware of any permanent effects of SSRI medications. If you smoke, try to quit. There's a Wikipedia article on the subject, and more info here, which suggest that while persistent effects from taking SSRIs are probably real, they're poorly understood. Even your mood can play a part.Other factors that can affect your sexual function include:Certain health conditions put you at increased risk of developing ED. I've never heard it mentioned from any clinicians I've worked with. Get our free guide when you sign up for our newsletter.Zainol, M, Sidi, H, Kuma, J, Das, S, Ismail, SB, Hatta, MH, Baharuddin, N, Ravindran, A. Kloner, R. ”Erectile Dysfunction and Hypertension.” For instance, you may be able to take another Zoloft, depression, and anxiety are only a few of the things that can cause ED. Smoking, drinking, and drug use can be part of the problem. It often requires several adjustments of medication and dosage before settling on the right ones.Your doctor may suggest other remedies if you find that your ED is not caused by depression or Zoloft. But many antidepressants can cause low sex drive and erectile dysfunction - or make them worse. This medication has been found to counter SSRI-induced sexual dysfunction, boost sexual drive and arousal, and increase the intensity or duration of an orgasm. They can also answer any questions you may have, such as:What antidepressants are least likely to cause sexual side effects?Any antidepressant can cause sexual problems. "Persistent" effects, sure, i.e., those that hang around for a while--sometimes years--after you stop taking the medication, but not permanent. Let your primary care physician or a specialist (like a cardiologist or psychiatrist) know that this is something that's bothering you, and then you can discuss all the possible remedies so you can find the relief that you deserve. Zoloft may also cause ED, however. Adding a drug. A lower dosage may reduce the drug’s effects on your sexual function. If they agree, they may adjust your dosage. Healthline Media does not provide medical advice, diagnosis, or treatment. I'm not aware of any permanent effects of SSRI medications. Some of them suggest that these drugs can do the following:Nitric oxide relaxes your muscles and blood vessels, which allows enough blood to flow to your sexual organs. ED is a complicated problem and multiple factors may be triggering it. A word of caution: Do not abruptly stop taking your Zoloft; this can cause uncomfortable

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